+Open data
-Basic information
Entry | Database: PDB / ID: 5yis | ||||||
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Title | Crystal Structure of AnkB LIR/LC3B complex | ||||||
Components |
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Keywords | PROTEIN BINDING / Autophagy | ||||||
Function / homology | Function and homology information Receptor Mediated Mitophagy / protein localization to T-tubule / atrial cardiac muscle cell to AV node cell communication / SA node cell to atrial cardiac muscle cell communication / regulation of calcium ion transmembrane transporter activity / positive regulation of calcium ion transmembrane transporter activity / TBC/RABGAPs / Macroautophagy / Pexophagy / protein localization to M-band ...Receptor Mediated Mitophagy / protein localization to T-tubule / atrial cardiac muscle cell to AV node cell communication / SA node cell to atrial cardiac muscle cell communication / regulation of calcium ion transmembrane transporter activity / positive regulation of calcium ion transmembrane transporter activity / TBC/RABGAPs / Macroautophagy / Pexophagy / protein localization to M-band / PINK1-PRKN Mediated Mitophagy / positive regulation of potassium ion transmembrane transporter activity / T-tubule organization / SA node cell action potential / membrane depolarization during SA node cell action potential / protein localization to organelle / paranodal junction assembly / mucus secretion / regulation of SA node cell action potential / regulation of atrial cardiac muscle cell action potential / phosphorylation-dependent protein binding / positive regulation of cation channel activity / atrial cardiac muscle cell action potential / protein localization to endoplasmic reticulum / KEAP1-NFE2L2 pathway / sarcoplasmic reticulum calcium ion transport / cytoskeletal anchor activity / atrial septum development / positive regulation of potassium ion transport / costamere / ventricular cardiac muscle cell action potential / regulation of release of sequestered calcium ion into cytosol / response to methylmercury / positive regulation of calcium ion transport / phosphatidylethanolamine binding / regulation of ventricular cardiac muscle cell membrane repolarization / M band / regulation of cardiac muscle contraction by calcium ion signaling / regulation of cardiac muscle cell contraction / protein localization to cell surface / cellular response to nitrogen starvation / Interaction between L1 and Ankyrins / A band / microtubule associated complex / positive regulation of mucus secretion / autolysosome / spectrin binding / regulation of heart rate by cardiac conduction / axoneme / regulation of calcium ion transport / autophagosome membrane / autophagosome maturation / intercalated disc / mitophagy / autophagosome assembly / regulation of cardiac muscle contraction / autophagosome / regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion / endomembrane system / COPI-mediated anterograde transport / T-tubule / regulation of heart rate / cellular response to starvation / tubulin binding / protein localization to plasma membrane / establishment of localization in cell / mitochondrial membrane / regulation of protein stability / recycling endosome / structural constituent of cytoskeleton / sarcolemma / Z disc / autophagy / intracellular calcium ion homeostasis / endocytosis / protein localization / protein transport / protein-macromolecule adaptor activity / ATPase binding / cytoplasmic vesicle / microtubule binding / basolateral plasma membrane / postsynaptic membrane / transmembrane transporter binding / microtubule / early endosome / lysosome / cytoskeleton / protein stabilization / neuron projection / apical plasma membrane / protein domain specific binding / axon / neuronal cell body / ubiquitin protein ligase binding / dendrite / positive regulation of gene expression / protein kinase binding / enzyme binding / mitochondrion Similarity search - Function | ||||||
Biological species | Mus musculus (house mouse) Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.201 Å | ||||||
Authors | Li, J. / Zhu, R. / Chen, K. / Zheng, H. / Yuan, C. / Zhang, H. / Wang, C. / Zhang, M. | ||||||
Funding support | Hong Kong, 1items
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Citation | Journal: Nat. Chem. Biol. / Year: 2018 Title: Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins. Authors: Li, J. / Zhu, R. / Chen, K. / Zheng, H. / Zhao, H. / Yuan, C. / Zhang, H. / Wang, C. / Zhang, M. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5yis.cif.gz | 128.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb5yis.ent.gz | 100 KB | Display | PDB format |
PDBx/mmJSON format | 5yis.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/yi/5yis ftp://data.pdbj.org/pub/pdb/validation_reports/yi/5yis | HTTPS FTP |
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-Related structure data
Related structure data | 5yipC 5yiqC 5yirC 1ugmS S: Starting model for refinement C: citing same article (ref.) |
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Similar structure data |
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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