IMMUNE SYSTEM / Domestic cats / MHC I / Feline immunodeficiency virus / CTL immunity
機能・相同性
機能・相同性情報
antigen processing and presentation of peptide antigen via MHC class I / viral budding via host ESCRT complex / antigen processing and presentation / MHC class I protein complex / peptide antigen assembly with MHC class II protein complex / MHC class II protein complex / phagocytic vesicle membrane / peptide antigen binding / antigen processing and presentation of exogenous peptide antigen via MHC class II / positive regulation of immune response ...antigen processing and presentation of peptide antigen via MHC class I / viral budding via host ESCRT complex / antigen processing and presentation / MHC class I protein complex / peptide antigen assembly with MHC class II protein complex / MHC class II protein complex / phagocytic vesicle membrane / peptide antigen binding / antigen processing and presentation of exogenous peptide antigen via MHC class II / positive regulation of immune response / positive regulation of T cell activation / MHC class II protein complex binding / late endosome membrane / viral nucleocapsid / nucleic acid binding / structural constituent of virion / immune response / lysosomal membrane / zinc ion binding / extracellular region 類似検索 - 分子機能
MHC class I, alpha chain, C-terminal / MHC_I C-terminus / MHC class I-like antigen recognition-like / Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / Beta-2-Microglobulin / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / MHC classes I/II-like antigen recognition protein ...MHC class I, alpha chain, C-terminal / MHC_I C-terminus / MHC class I-like antigen recognition-like / Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / Beta-2-Microglobulin / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / MHC classes I/II-like antigen recognition protein / Retroviral nucleocapsid Gag protein p24, C-terminal domain / Gag protein p24 C-terminal domain / Matrix protein, lentiviral and alpha-retroviral, N-terminal / Retrovirus capsid, C-terminal / Retrovirus capsid, N-terminal / zinc finger / Zinc knuckle / Zinc finger, CCHC-type superfamily / Zinc finger, CCHC-type / Zinc finger CCHC-type profile. / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / 2-Layer Sandwich / Mainly Beta / Alpha Beta 類似検索 - ドメイン・相同性
MHC class I antigen / Gag polyprotein / Beta-2-microglobulin 類似検索 - 構成要素
根拠: gel filtration, one MHC class I heavy chain, one B2-Microglobulin and one peptide
タイプ
名称
対称操作
数
identity operation
1_555
x,y,z
1
Buried area
4680 Å2
ΔGint
-15 kcal/mol
Surface area
19170 Å2
手法
PISA
単位格子
Length a, b, c (Å)
47.120, 82.640, 121.130
Angle α, β, γ (deg.)
90.00, 90.00, 90.00
Int Tables number
19
Space group name H-M
P212121
-
要素
#1: タンパク質
MHCclassIantigenalphachain
分子量: 31848.109 Da / 分子数: 1 / 断片: UNP residues 25-299 / 変異: W168S / 由来タイプ: 組換発現 詳細: This protein is the mutant of FLA-B*n06 and W residue was mutated into S residue 由来: (組換発現) Felis catus (イエネコ) / 遺伝子: FLA-I / 発現宿主: Escherichia coli (大腸菌) / 参照: UniProt: C6ZK72