登録情報 データベース : PDB / ID : 5xjb 構造の表示 ダウンロードとリンクタイトル The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-BeFx 要素Kinesin-like protein KIF2C 詳細 キーワード STRUCTURAL PROTEIN / Kinesin / Microtubule / tubulin / KIF2 / MCAK / depolymerization機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
postsynaptic cytoskeleton organization / regulation of chromosome segregation / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / establishment or maintenance of microtubule cytoskeleton polarity / Kinesins / metaphase chromosome alignment / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / COPI-dependent Golgi-to-ER retrograde traffic ... postsynaptic cytoskeleton organization / regulation of chromosome segregation / Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / establishment or maintenance of microtubule cytoskeleton polarity / Kinesins / metaphase chromosome alignment / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / Resolution of Sister Chromatid Cohesion / COPI-dependent Golgi-to-ER retrograde traffic / RHO GTPases Activate Formins / Separation of Sister Chromatids / microtubule plus-end / attachment of mitotic spindle microtubules to kinetochore / MHC class II antigen presentation / microtubule plus-end binding / microtubule depolymerization / microtubule motor activity / microtubule-based movement / mitotic metaphase chromosome alignment / regulation of neurotransmitter receptor localization to postsynaptic specialization membrane / chromosome, centromeric region / kinetochore / presynapse / postsynapse / cell division / glutamatergic synapse / ATP binding / nucleus / cytoplasm 類似検索 - 分子機能 : / Kinesin-like protein KIF2A-like, N-terminal / Kinesin-like protein / Kinesin motor domain signature. / Kinesin motor domain, conserved site / Kinesin motor domain / Kinesin motor domain profile. / Kinesin motor, catalytic domain. ATPase. / Kinesin motor domain / Kinesin motor domain superfamily / P-loop containing nucleoside triphosphate hydrolase 類似検索 - ドメイン・相同性 ADENOSINE-5'-DIPHOSPHATE / BERYLLIUM TRIFLUORIDE ION / Kinesin-like protein KIF2C 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 3.1 Å 詳細データ登録者 Ogawa, T. / Jiang, X. / Hirokawa, N. 資金援助 日本, 1件 詳細 詳細を隠す組織 認可番号 国 Ministriy of Education, Culture, Sports, Science and Technology 23000013, 16H06372 日本
引用ジャーナル : Cell Rep / 年 : 2017タイトル : Mechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation著者 : Ogawa, T. / Saijo, S. / Shimizu, N. / Jiang, X. / Hirokawa, N. 履歴 登録 2017年4月30日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2017年9月13日 Provider : repository / タイプ : Initial release改定 1.1 2017年9月27日 Group : Database references / カテゴリ : citationItem : _citation.journal_volume / _citation.page_first ... _citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title 改定 1.2 2023年11月22日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_label_asym_id
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