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Structure paper

TitleMechanism of Catalytic Microtubule Depolymerization via KIF2-Tubulin Transitional Conformation
Journal, issue, pagesCell Rep, Vol. 20, Page 2626-2638, Year 2017
Publish dateApr 30, 2017 (structure data deposition date)
AuthorsOgawa, T. / Saijo, S. / Shimizu, N. / Jiang, X. / Hirokawa, N.
External linksCell Rep / PubMed:28903043
MethodsX-ray diffraction
Resolution3.1 - 3.43 Å
Structure data

PDB-5xja:
The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-AlFx
Method: X-RAY DIFFRACTION / Resolution: 3.43 Å

PDB-5xjb:
The Crystal Structure of the Minimal Core Domain of the Microtubule Depolymerizer KIF2C Complexed with ADP-Mg-BeFx
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-AF3:
ALUMINUM FLUORIDE

ChemComp-HOH:
WATER

ChemComp-BEF:
BERYLLIUM TRIFLUORIDE ION

Source
  • mus musculus (house mouse)
KeywordsSTRUCTURAL PROTEIN / Kinesin / Microtubule / tubulin / KIF2 / MCAK / depolymerization

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