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Yorodumi- PDB-5usr: Crystal structure of human NFS1-ISD11 in complex with E. coli acy... -
+Open data
-Basic information
Entry | Database: PDB / ID: 5usr | ||||||||||||
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Title | Crystal structure of human NFS1-ISD11 in complex with E. coli acyl-carrier protein at 3.09 angstroms | ||||||||||||
Components |
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Keywords | TRANSFERASE / LYR / Fe-S cluster assembly / NFS1 / acyl-carrier protein | ||||||||||||
Function / homology | Function and homology information molybdopterin cofactor metabolic process / Molybdenum cofactor biosynthesis / [4Fe-4S] cluster assembly / iron incorporation into metallo-sulfur cluster / L-cysteine desulfurase complex / Mitochondrial iron-sulfur cluster biogenesis / mitochondrial [2Fe-2S] assembly complex / Maturation of TCA enzymes and regulation of TCA cycle / cysteine desulfurase / cysteine desulfurase activity ...molybdopterin cofactor metabolic process / Molybdenum cofactor biosynthesis / [4Fe-4S] cluster assembly / iron incorporation into metallo-sulfur cluster / L-cysteine desulfurase complex / Mitochondrial iron-sulfur cluster biogenesis / mitochondrial [2Fe-2S] assembly complex / Maturation of TCA enzymes and regulation of TCA cycle / cysteine desulfurase / cysteine desulfurase activity / Mo-molybdopterin cofactor biosynthetic process / iron-sulfur cluster assembly complex / [2Fe-2S] cluster assembly / lipid biosynthetic process / iron-sulfur cluster assembly / lipid A biosynthetic process / iron-sulfur cluster binding / phosphopantetheine binding / acyl binding / acyl carrier activity / fatty acid biosynthetic process / pyridoxal phosphate binding / nuclear body / mitochondrial matrix / response to xenobiotic stimulus / centrosome / lipid binding / protein homodimerization activity / mitochondrion / nucleoplasm / nucleus / metal ion binding / cytoplasm / cytosol Similarity search - Function | ||||||||||||
Biological species | Homo sapiens (human) Escherichia coli (E. coli) | ||||||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.09 Å | ||||||||||||
Authors | Cory, S.A. / Barondeau, D.P. | ||||||||||||
Funding support | United States, 3items
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Citation | Journal: Proc. Natl. Acad. Sci. U.S.A. / Year: 2017 Title: Structure of human Fe-S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP-ISD11 interactions. Authors: Cory, S.A. / Van Vranken, J.G. / Brignole, E.J. / Patra, S. / Winge, D.R. / Drennan, C.L. / Rutter, J. / Barondeau, D.P. | ||||||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 5usr.cif.gz | 815.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb5usr.ent.gz | 677.9 KB | Display | PDB format |
PDBx/mmJSON format | 5usr.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 5usr_validation.pdf.gz | 1 MB | Display | wwPDB validaton report |
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Full document | 5usr_full_validation.pdf.gz | 1.1 MB | Display | |
Data in XML | 5usr_validation.xml.gz | 70 KB | Display | |
Data in CIF | 5usr_validation.cif.gz | 91.9 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/us/5usr ftp://data.pdbj.org/pub/pdb/validation_reports/us/5usr | HTTPS FTP |
-Related structure data
Related structure data | 3lvmS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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