Entry | Database: PDB / ID: 5udd |
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Title | Crystal Structure of RSV F B9320 Bound to MEDI8897 |
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Components | - Fusion glycoprotein F0
- MEDI8897 Fab Heavy Chain
- MEDI8897 Fab Light Chain
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Keywords | Viral Protein/Immune System / immune system / antibody / fusion glycoprotein / virus / Viral Protein-Immune System complex |
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Function / homology | Precursor fusion glycoprotein F0, Paramyxoviridae / Fusion glycoprotein F0 / host cell Golgi membrane / entry receptor-mediated virion attachment to host cell / fusion of virus membrane with host plasma membrane / host cell plasma membrane / virion membrane / plasma membrane / Fusion glycoprotein F0 Function and homology information |
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Biological species | Human Respiratory syncytial virus 9320
Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / molecular replacement / Resolution: 4.3 Å |
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Authors | McLellan, J.S. |
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Citation | Journal: Sci Transl Med / Year: 2017 Title: A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants. Authors: Zhu, Q. / McLellan, J.S. / Kallewaard, N.L. / Ulbrandt, N.D. / Palaszynski, S. / Zhang, J. / Moldt, B. / Khan, A. / Svabek, C. / McAuliffe, J.M. / Wrapp, D. / Patel, N.K. / Cook, K.E. / ...Authors: Zhu, Q. / McLellan, J.S. / Kallewaard, N.L. / Ulbrandt, N.D. / Palaszynski, S. / Zhang, J. / Moldt, B. / Khan, A. / Svabek, C. / McAuliffe, J.M. / Wrapp, D. / Patel, N.K. / Cook, K.E. / Richter, B.W.M. / Ryan, P.C. / Yuan, A.Q. / Suzich, J.A. |
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History | Deposition | Dec 26, 2016 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | May 17, 2017 | Provider: repository / Type: Initial release |
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Revision 1.1 | Oct 4, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
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