登録情報 | データベース: PDB / ID: 5twy |
---|
タイトル | Structure of Maternal Embryonic Leucine Zipper Kinase |
---|
要素 | Maternal embryonic leucine zipper kinase |
---|
キーワード | Transferase/Transferase Inhibitor / kinase / inhibitor / breast cancer / Transferase-Transferase Inhibitor complex |
---|
機能・相同性 | 機能・相同性情報
neural precursor cell proliferation / intrinsic apoptotic signaling pathway in response to oxidative stress / hemopoiesis / non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / G2/M transition of mitotic cell cycle / cell cortex / cell population proliferation / protein autophosphorylation / non-specific serine/threonine protein kinase ...neural precursor cell proliferation / intrinsic apoptotic signaling pathway in response to oxidative stress / hemopoiesis / non-specific protein-tyrosine kinase / non-membrane spanning protein tyrosine kinase activity / G2/M transition of mitotic cell cycle / cell cortex / cell population proliferation / protein autophosphorylation / non-specific serine/threonine protein kinase / positive regulation of apoptotic process / protein serine kinase activity / protein serine/threonine kinase activity / lipid binding / calcium ion binding / apoptotic process / ATP binding / membrane / plasma membrane / cytoplasm類似検索 - 分子機能 Maternal embryonic leucine zipper kinase, catalytic domain / : / Maternal embryonic leucine zipper kinase, UBA domain / Kinase associated domain 1 (KA1) / Kinase associated domain 1 / Kinase associated domain 1 (KA1) profile. / KA1 domain/Ssp2, C-terminal / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain ...Maternal embryonic leucine zipper kinase, catalytic domain / : / Maternal embryonic leucine zipper kinase, UBA domain / Kinase associated domain 1 (KA1) / Kinase associated domain 1 / Kinase associated domain 1 (KA1) profile. / KA1 domain/Ssp2, C-terminal / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily類似検索 - ドメイン・相同性 Chem-7LY / Maternal embryonic leucine zipper kinase類似検索 - 構成要素 |
---|
生物種 | Homo sapiens (ヒト) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.91 Å |
---|
データ登録者 | Seo, H.-S. / Dhe-Paganon, S. |
---|
引用 | ジャーナル: Elife / 年: 2017 タイトル: MELK is not necessary for the proliferation of basal-like breast cancer cells. 著者: Huang, H.T. / Seo, H.S. / Zhang, T. / Wang, Y. / Jiang, B. / Li, Q. / Buckley, D.L. / Nabet, B. / Roberts, J.M. / Paulk, J. / Dastjerdi, S. / Winter, G.E. / McLauchlan, H. / Moran, J. / ...著者: Huang, H.T. / Seo, H.S. / Zhang, T. / Wang, Y. / Jiang, B. / Li, Q. / Buckley, D.L. / Nabet, B. / Roberts, J.M. / Paulk, J. / Dastjerdi, S. / Winter, G.E. / McLauchlan, H. / Moran, J. / Bradner, J.E. / Eck, M.J. / Dhe-Paganon, S. / Zhao, J.J. / Gray, N.S. |
---|
履歴 | 登録 | 2016年11月15日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2017年11月22日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2019年6月5日 | Group: Data collection / Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.journal_volume / _citation.pdbx_database_id_DOI / _citation.pdbx_database_id_PubMed / _citation.title / _citation.year |
---|
改定 1.2 | 2024年3月6日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
---|
|
---|