登録情報 | データベース: PDB / ID: 5svx |
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タイトル | MORC3 CW in complex with histone H3K4me3 |
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要素 | - H3K4me3
- MORC family CW-type zinc finger protein 3
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キーワード | TRANSCRIPTION / reader / histone / chromatin / methylation / methyllysine |
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機能・相同性 | 機能・相同性情報
negative regulation of interferon-beta production / maintenance of protein location in nucleus / antiviral innate immune response / Chromatin modifying enzymes / epigenetic regulation of gene expression / negative regulation of fibroblast proliferation / methylated histone binding / telomere organization / RNA Polymerase I Promoter Opening / Interleukin-7 signaling ...negative regulation of interferon-beta production / maintenance of protein location in nucleus / antiviral innate immune response / Chromatin modifying enzymes / epigenetic regulation of gene expression / negative regulation of fibroblast proliferation / methylated histone binding / telomere organization / RNA Polymerase I Promoter Opening / Interleukin-7 signaling / Assembly of the ORC complex at the origin of replication / DNA methylation / Condensation of Prophase Chromosomes / post-embryonic development / ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression / SIRT1 negatively regulates rRNA expression / Chromatin modifications during the maternal to zygotic transition (MZT) / HCMV Late Events / PRC2 methylates histones and DNA / Defective pyroptosis / HDACs deacetylate histones / RNA Polymerase I Promoter Escape / Transcriptional regulation by small RNAs / Formation of the beta-catenin:TCF transactivating complex / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / NoRC negatively regulates rRNA expression / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / B-WICH complex positively regulates rRNA expression / HDMs demethylate histones / PKMTs methylate histone lysines / PML body / Meiotic recombination / RMTs methylate histone arginines / Pre-NOTCH Transcription and Translation / nuclear matrix / Activation of anterior HOX genes in hindbrain development during early embryogenesis / HCMV Early Events / Transcriptional regulation of granulopoiesis / structural constituent of chromatin / positive regulation of cellular senescence / nucleosome / nucleosome assembly / chromatin organization / protein-macromolecule adaptor activity / RUNX1 regulates transcription of genes involved in differentiation of HSCs / Factors involved in megakaryocyte development and platelet production / gene expression / HATs acetylate histones / Senescence-Associated Secretory Phenotype (SASP) / peptidyl-serine phosphorylation / Oxidative Stress Induced Senescence / Estrogen-dependent gene expression / protein stabilization / cadherin binding / protein heterodimerization activity / Amyloid fiber formation / protein phosphorylation / chromatin / negative regulation of transcription by RNA polymerase II / ATP hydrolysis activity / protein-containing complex / DNA binding / RNA binding / zinc ion binding / extracellular exosome / extracellular region / nucleoplasm / membrane / nucleus類似検索 - 分子機能 MICRORCHIDIA ATPase family / Morc, S5 domain 2-like / Morc6 ribosomal protein S5 domain 2-like / Herpes Virus-1 - #100 / Zinc finger, CW-type / CW-type Zinc Finger / Zinc finger CW-type profile. / Herpes Virus-1 / Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase / Histone H3 signature 1. ...MICRORCHIDIA ATPase family / Morc, S5 domain 2-like / Morc6 ribosomal protein S5 domain 2-like / Herpes Virus-1 - #100 / Zinc finger, CW-type / CW-type Zinc Finger / Zinc finger CW-type profile. / Herpes Virus-1 / Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase / Histone H3 signature 1. / Histidine kinase/HSP90-like ATPase superfamily / Histone H3 signature 2. / Histone H3 / Histone H3/CENP-A / Histone H2A/H2B/H3 / Core histone H2A/H2B/H3/H4 / Histone-fold / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Histone H3.1 / MORC family CW-type zinc finger protein 3類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 1.56 Å |
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データ登録者 | Tong, Q. / Andrews, F.H. / Kutateladze, T.G. |
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引用 | ジャーナル: Cell Rep / 年: 2016 タイトル: Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase. 著者: Andrews, F.H. / Tong, Q. / Sullivan, K.D. / Cornett, E.M. / Zhang, Y. / Ali, M. / Ahn, J. / Pandey, A. / Guo, A.H. / Strahl, B.D. / Costello, J.C. / Espinosa, J.M. / Rothbart, S.B. / Kutateladze, T.G. |
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履歴 | 登録 | 2016年8月8日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2016年10月5日 | Provider: repository / タイプ: Initial release |
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