登録情報 | データベース: PDB / ID: 5ola |
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タイトル | Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM |
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要素 | - DNA (30-MER)
- DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3')
- DNA-directed RNA polymerase, mitochondrial
- RNA (5'-R(P*GP*CP*GP*GP*CP*GP*CP*GP*C)-3')
- Transcription elongation factor, mitochondrial
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キーワード | TRANSCRIPTION / Elongation Factor / Mitochondria / Resolvase / RNA Polymerase |
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機能・相同性 | 機能・相同性情報
transcription elongation by mitochondrial RNA polymerase / Mitochondrial transcription initiation / mitochondrial DNA-directed RNA polymerase complex / mitochondrial promoter sequence-specific DNA binding / transcription initiation at mitochondrial promoter / mitochondrial transcription / DNA primase activity / oxidative phosphorylation / DNA polymerase processivity factor activity / mitochondrial nucleoid ...transcription elongation by mitochondrial RNA polymerase / Mitochondrial transcription initiation / mitochondrial DNA-directed RNA polymerase complex / mitochondrial promoter sequence-specific DNA binding / transcription initiation at mitochondrial promoter / mitochondrial transcription / DNA primase activity / oxidative phosphorylation / DNA polymerase processivity factor activity / mitochondrial nucleoid / Transcriptional activation of mitochondrial biogenesis / DNA-directed 5'-3' RNA polymerase activity / DNA-directed RNA polymerase / 3'-5'-RNA exonuclease activity / sequence-specific DNA binding / mitochondrial matrix / ribonucleoprotein complex / protein-containing complex / mitochondrion / RNA binding類似検索 - 分子機能 Transcription elongation factor, mitochondrial / Helix-hairpin-helix motif / DNA-directed RNA polymerase, N-terminal / DNA-directed RNA polymerase, N-terminal domain superfamily / DNA-directed RNA polymerase N-terminal / Bacteriophage-type RNA polymerase family active site signature 1. / DNA-directed RNA polymerase N-terminal / DNA-directed RNA polymerase, phage-type / : / DNA-dependent RNA polymerase ...Transcription elongation factor, mitochondrial / Helix-hairpin-helix motif / DNA-directed RNA polymerase, N-terminal / DNA-directed RNA polymerase, N-terminal domain superfamily / DNA-directed RNA polymerase N-terminal / Bacteriophage-type RNA polymerase family active site signature 1. / DNA-directed RNA polymerase N-terminal / DNA-directed RNA polymerase, phage-type / : / DNA-dependent RNA polymerase / Bacteriophage-type RNA polymerase family active site signature 2. / RuvA domain 2-like / Tetratricopeptide-like helical domain superfamily / Ribonuclease H superfamily / Ribonuclease H-like superfamily / DNA/RNA polymerase superfamily類似検索 - ドメイン・相同性 DNA / DNA (> 10) / RNA / RNA (> 10) / DNA-directed RNA polymerase, mitochondrial / Transcription elongation factor, mitochondrial類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) synthetic construct (人工物) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.904 Å |
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データ登録者 | Hillen, H.S. / Parshin, A.V. / Agaronyan, K. / Morozov, Y. / Graber, J.J. / Chernev, A. / Schwinghammer, K. / Urlaub, H. / Anikin, M. / Cramer, P. / Temiakov, D. |
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資金援助 | 米国, ドイツ, 5件 組織 | 認可番号 | 国 |
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National Institutes of Health | RO1 GM104231 | 米国 | German Research Foundation | SFB860 | ドイツ | German Research Foundation | SPP1935 | ドイツ | European Research Council | 693023 | ドイツ | Volkswagen Foundation | | ドイツ |
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引用 | ジャーナル: Cell / 年: 2017 タイトル: Mechanism of Transcription Anti-termination in Human Mitochondria. 著者: Hillen, H.S. / Parshin, A.V. / Agaronyan, K. / Morozov, Y.I. / Graber, J.J. / Chernev, A. / Schwinghammer, K. / Urlaub, H. / Anikin, M. / Cramer, P. / Temiakov, D. |
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履歴 | 登録 | 2017年7月27日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2017年10月18日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年10月25日 | Group: Database references / カテゴリ: citation / citation_author Item: _citation.country / _citation.journal_abbrev ..._citation.country / _citation.journal_abbrev / _citation.journal_id_ASTM / _citation.journal_id_CSD / _citation.journal_id_ISSN / _citation.pdbx_database_id_PubMed / _citation.title / _citation_author.name |
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改定 1.2 | 2017年11月29日 | Group: Database references / カテゴリ: citation Item: _citation.journal_volume / _citation.page_first / _citation.page_last |
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改定 1.3 | 2024年1月17日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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