登録情報 | データベース: PDB / ID: 5fb6 |
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タイトル | Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering |
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要素 | - Insulin Chain A
- Insulin Chain B
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キーワード | HORMONE / cubic insulin |
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機能・相同性 | 機能・相同性情報
positive regulation of lipoprotein lipase activity / Insulin processing / IRS activation / Signal attenuation / Insulin receptor signalling cascade / Signaling by Insulin receptor / Synthesis, secretion, and deacylation of Ghrelin / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / Insulin receptor recycling / glycoprotein biosynthetic process ...positive regulation of lipoprotein lipase activity / Insulin processing / IRS activation / Signal attenuation / Insulin receptor signalling cascade / Signaling by Insulin receptor / Synthesis, secretion, and deacylation of Ghrelin / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / Insulin receptor recycling / glycoprotein biosynthetic process / response to L-arginine / lactate biosynthetic process / positive regulation of glucose metabolic process / positive regulation of fatty acid biosynthetic process / lipoprotein biosynthetic process / COPI-mediated anterograde transport / negative regulation of glycogen catabolic process / positive regulation of nitric oxide mediated signal transduction / negative regulation of fatty acid metabolic process / negative regulation of feeding behavior / lipid biosynthetic process / positive regulation of respiratory burst / negative regulation of acute inflammatory response / alpha-beta T cell activation / positive regulation of dendritic spine maintenance / negative regulation of respiratory burst involved in inflammatory response / negative regulation of protein secretion / negative regulation of gluconeogenesis / positive regulation of insulin receptor signaling pathway / positive regulation of glycogen biosynthetic process / fatty acid homeostasis / negative regulation of lipid catabolic process / regulation of protein localization to plasma membrane / nitric oxide-cGMP-mediated signaling / negative regulation of reactive oxygen species biosynthetic process / insulin-like growth factor receptor binding / neuron projection maintenance / positive regulation of mitotic nuclear division / positive regulation of cytokine production / positive regulation of glycolytic process / positive regulation of DNA replication / acute-phase response / positive regulation of protein secretion / positive regulation of D-glucose import / insulin receptor binding / wound healing / hormone activity / negative regulation of protein catabolic process / positive regulation of protein localization to nucleus / vasodilation / glucose metabolic process / insulin receptor signaling pathway / glucose homeostasis / protease binding / positive regulation of canonical NF-kappaB signal transduction / positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / positive regulation of MAPK cascade / positive regulation of cell migration / G protein-coupled receptor signaling pathway / negative regulation of gene expression / positive regulation of cell population proliferation / extracellular space / identical protein binding類似検索 - 分子機能 Insulin / Insulin family / Insulin-like / Insulin/IGF/Relaxin family / Insulin / insulin-like growth factor / relaxin family. / Insulin, conserved site / Insulin family signature. / Insulin-like superfamily類似検索 - ドメイン・相同性 |
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生物種 |  Sus scrofa (ブタ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.901 Å |
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データ登録者 | Roedig, P. / Duman, R. / Sanchez-Weatherby, J. / Vartiainen, I. / Burkhardt, A. / Warmer, M. / David, C. / Wagner, A. / Meents, A. |
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資金援助 | スイス, ドイツ, 2件 組織 | 認可番号 | 国 |
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European Community | 290605 | スイス | Helmholtz Association | VH-VI-403 | ドイツ |
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引用 | ジャーナル: J.Appl.Crystallogr. / 年: 2016 タイトル: Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering. 著者: Roedig, P. / Duman, R. / Sanchez-Weatherby, J. / Vartiainen, I. / Burkhardt, A. / Warmer, M. / David, C. / Wagner, A. / Meents, A. |
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履歴 | 登録 | 2015年12月14日 | 登録サイト: RCSB / 処理サイト: PDBE |
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改定 1.0 | 2016年6月15日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2016年6月22日 | Group: Database references |
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改定 1.2 | 2024年1月10日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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改定 1.3 | 2024年11月20日 | Group: Structure summary カテゴリ: pdbx_entry_details / pdbx_modification_feature |
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