- PDB-5f8p: A Novel Inhibitor of the Obesity-Related Protein FTO -
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基本情報
登録情報
データベース: PDB / ID: 5f8p
タイトル
A Novel Inhibitor of the Obesity-Related Protein FTO
要素
Alpha-ketoglutarate-dependent dioxygenase FTO
キーワード
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Fat mass and obesity associated(FTO) protein / small molecule / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
機能・相同性
機能・相同性情報
regulation of white fat cell proliferation / tRNA demethylase activity / Reversal of alkylation damage by DNA dioxygenases / mRNA N6-methyladenine demethylase / mRNA N6-methyladenosine dioxygenase activity / regulation of respiratory system process / regulation of lipid storage / : / regulation of brown fat cell differentiation / oxidative RNA demethylation ...regulation of white fat cell proliferation / tRNA demethylase activity / Reversal of alkylation damage by DNA dioxygenases / mRNA N6-methyladenine demethylase / mRNA N6-methyladenosine dioxygenase activity / regulation of respiratory system process / regulation of lipid storage / : / regulation of brown fat cell differentiation / oxidative RNA demethylation / : / oxidative RNA demethylase activity / broad specificity oxidative DNA demethylase activity / 酸化還元酵素; 電子対供与作用を持つ; 分子酸素を取り込むないしは分子酸素を還元する; 2-オキソグルタル酸類を片方の電子供与体とする; 酸素分をそれぞれの電子供与体に取り込む / RNA repair / DNA alkylation repair / temperature homeostasis / mRNA destabilization / regulation of multicellular organism growth / adipose tissue development / ferrous iron binding / transferase activity / nuclear speck / intracellular membrane-bounded organelle / nucleoplasm / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能