登録情報 | データベース: PDB / ID: 5e0o |
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タイトル | Brugia malayi Trehalose-6 Phosphate Phosphatase in complex with PEG at the active site. |
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要素 | Trehalose-phosphatase |
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キーワード | HYDROLASE / HAD / Complex / Phosphatase |
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機能・相同性 | 機能・相同性情報
trehalose-phosphatase / carbohydrate derivative catabolic process / trehalose-phosphatase activity / trehalose biosynthetic process / dephosphorylation / magnesium ion binding類似検索 - 分子機能 Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #1800 / Alpha-Beta Plaits - #3080 / Trehalose-6-phosphate phosphatase, helical bundle domain / : / Trehalose-6-phosphate phosphatase N-terminal helical bundle domain / Trehalose-6-phosphate phosphatase, C-terminal / HAD superfamily/HAD-like / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / HAD superfamily / HAD-like superfamily ...Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #1800 / Alpha-Beta Plaits - #3080 / Trehalose-6-phosphate phosphatase, helical bundle domain / : / Trehalose-6-phosphate phosphatase N-terminal helical bundle domain / Trehalose-6-phosphate phosphatase, C-terminal / HAD superfamily/HAD-like / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / HAD superfamily / HAD-like superfamily / Alpha-Beta Plaits / Up-down Bundle / Rossmann fold / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 DI(HYDROXYETHYL)ETHER / Trehalose-phosphatase類似検索 - 構成要素 |
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生物種 | Brugia malayi (マレー糸状虫) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3 Å |
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データ登録者 | Agarwal, A. / Misra-Bhattacharya, S. / Ravishankar, R. |
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資金援助 | インド, 1件 組織 | 認可番号 | 国 |
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Council of Scientific and Industrial Research | BSC0104 | インド |
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引用 | #1: ジャーナル: PLoS Pathog. / 年: 2014タイトル: Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. 著者: Farelli, J.D. / Galvin, B.D. / Li, Z. / Liu, C. / Aono, M. / Garland, M. / Hallett, O.E. / Causey, T.B. / Ali-Reynolds, A. / Saltzberg, D.J. / Carlow, C.K. / Dunaway-Mariano, D. / Allen, K.N. |
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履歴 | 登録 | 2015年9月29日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2015年10月28日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / citation / database_2 / pdbx_initial_refinement_model / pdbx_prerelease_seq / pdbx_struct_oper_list Item: _citation.journal_id_CSD / _database_2.pdbx_DOI ..._citation.journal_id_CSD / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation |
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