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| Title | Structure of the Trehalose-6-phosphate Phosphatase from Brugia malayi Reveals Key Design Principles for Anthelmintic Drugs. |
|---|---|
| Journal, issue, pages | Plos Pathog., Vol. 10, Page e1004245-e1004245, Year 2014 |
| Publish date | Jan 15, 2014 (structure data deposition date) |
Authors | Farelli, J.D. / Galvin, B.D. / Li, Z. / Liu, C. / Aono, M. / Garland, M. / Hallett, O.E. / Causey, T.B. / Ali-Reynolds, A. / Saltzberg, D.J. ...Farelli, J.D. / Galvin, B.D. / Li, Z. / Liu, C. / Aono, M. / Garland, M. / Hallett, O.E. / Causey, T.B. / Ali-Reynolds, A. / Saltzberg, D.J. / Carlow, C.K. / Dunaway-Mariano, D. / Allen, K.N. |
External links | Plos Pathog. / PubMed:24992307 |
| Methods | X-ray diffraction |
| Resolution | 3 Å |
| Structure data | ![]() PDB-4ofz: |
| Chemicals | ![]() ChemComp-MG: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE / HAD superfamily/Rossmann fold / trehalose-6-phosphate phosphohydrolase |
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brugia malayi (agent of lymphatic filariasis)
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