Entry | Database: PDB / ID: 5dep |
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Title | Structure of Pseudomonas aeruginosa LpxA in complex with UDP-GlcNAc |
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Components | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase |
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Keywords | TRANSFERASE / Acyltransferase Catalytic Domain / Fatty Acids / Lipid A / Substrate Specificity / Uridine Diphosphate N-Acetylglucosamine / Hydrocarbon Rulers |
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Function / homology | Function and homology information
acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase / acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity / lipid A biosynthetic process / cytoplasmSimilarity search - Function Udp N-acetylglucosamine O-acyltransferase; Domain 2 / Udp N-acetylglucosamine O-acyltransferase, C-terminal domain / UDP N-acetylglucosamine O-acyltransferase, C-terminal / UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily / Udp N-acetylglucosamine O-acyltransferase; Domain 2 / Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase / Hexapeptide transferase, conserved site / Hexapeptide-repeat containing-transferases signature. / Hexapeptide repeat proteins / UDP N-Acetylglucosamine Acyltransferase; domain 1 ...Udp N-acetylglucosamine O-acyltransferase; Domain 2 / Udp N-acetylglucosamine O-acyltransferase, C-terminal domain / UDP N-acetylglucosamine O-acyltransferase, C-terminal / UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily / Udp N-acetylglucosamine O-acyltransferase; Domain 2 / Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase / Hexapeptide transferase, conserved site / Hexapeptide-repeat containing-transferases signature. / Hexapeptide repeat proteins / UDP N-Acetylglucosamine Acyltransferase; domain 1 / Hexapeptide repeat / Bacterial transferase hexapeptide (six repeats) / Trimeric LpxA-like superfamily / 3 Solenoid / Up-down Bundle / Mainly Beta / Mainly AlphaSimilarity search - Domain/homology PHOSPHATE ION / URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE / Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferaseSimilarity search - Component |
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Biological species | ![](img/tx_bacteria.gif) Pseudomonas aeruginosa (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.16 Å |
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Authors | Smith, E.W. / Chen, Y. |
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Citation | Journal: Biochemistry / Year: 2015 Title: Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity. Authors: Smith, E.W. / Zhang, X. / Behzadi, C. / Andrews, L.D. / Cohen, F. / Chen, Y. |
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History | Deposition | Aug 25, 2015 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Sep 16, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Sep 30, 2015 | Group: Database references |
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Revision 1.2 | Oct 14, 2015 | Group: Database references |
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Revision 1.3 | Nov 22, 2017 | Group: Database references / Derived calculations / Refinement description Category: citation / pdbx_struct_oper_list / software Item: _citation.journal_id_CSD / _pdbx_struct_oper_list.symmetry_operation |
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Revision 1.4 | Mar 6, 2024 | Group: Data collection / Database references / Category: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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