Entry Database : PDB / ID : 4yrd Structure visualization Downloads & linksTitle Crystal structure of CapF with inhibitor 3-isopropenyl-tropolone ComponentsCapsular polysaccharide synthesis enzyme Cap5F Details Keywords OXIDOREDUCTASE/INHIBITOR / CapF cupin capsular polysaccharide staphylococcus aureus / OXIDOREDUCTASE-INHIBITOR complexFunction / homology Function and homology informationFunction Domain/homology Component
: / NAD-dependent epimerase/dehydratase / NAD dependent epimerase/dehydratase family / RmlC-like cupin domain superfamily / Jelly Rolls / RmlC-like jelly roll fold / NAD(P)-binding Rossmann-like Domain / Jelly Rolls / NAD(P)-binding domain superfamily / Sandwich ... : / NAD-dependent epimerase/dehydratase / NAD dependent epimerase/dehydratase family / RmlC-like cupin domain superfamily / Jelly Rolls / RmlC-like jelly roll fold / NAD(P)-binding Rossmann-like Domain / Jelly Rolls / NAD(P)-binding domain superfamily / Sandwich / Rossmann fold / 3-Layer(aba) Sandwich / Mainly Beta / Alpha Beta Similarity search - Domain/homologyBiological species Staphylococcus aureus (bacteria)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.44 Å DetailsAuthors Nakano, K. / Chigira, T. / Miyafusa, T. / Nagatoishi, S. / Caaveiro, J.M.M. / Tsumoto, K. CitationJournal : Sci Rep / Year : 2015Title : Discovery and characterization of natural tropolones as inhibitors of the antibacterial target CapF from Staphylococcus aureus.Authors : Nakano, K. / Chigira, T. / Miyafusa, T. / Nagatoishi, S. / Caaveiro, J.M. / Tsumoto, K. History Deposition Mar 15, 2015 Deposition site : RCSB / Processing site : PDBJRevision 1.0 Oct 21, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Nov 4, 2015 Group : Database referencesRevision 1.2 Feb 5, 2020 Group : Data collection / Derived calculations / Category : diffrn_source / pdbx_struct_oper_listItem : _diffrn_source.pdbx_synchrotron_site / _pdbx_struct_oper_list.symmetry_operationRevision 1.3 Nov 8, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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