Entry | Database: PDB / ID: 4wbk |
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Title | The 1.37 angstrom X-ray structure of the human heart fatty acid-binding protein complexed with stearic acid |
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Components | Fatty acid-binding protein, heart |
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Keywords | LIPID BINDING PROTEIN / LIPID-BINDING PROTEIN |
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Function / homology | Function and homology information
positive regulation of long-chain fatty acid import into cell / regulation of phosphatidylcholine biosynthetic process / regulation of fatty acid oxidation / positive regulation of phospholipid biosynthetic process / intracellular lipid transport / oleic acid binding / phospholipid homeostasis / long-chain fatty acid binding / Triglyceride catabolism / long-chain fatty acid transport ...positive regulation of long-chain fatty acid import into cell / regulation of phosphatidylcholine biosynthetic process / regulation of fatty acid oxidation / positive regulation of phospholipid biosynthetic process / intracellular lipid transport / oleic acid binding / phospholipid homeostasis / long-chain fatty acid binding / Triglyceride catabolism / long-chain fatty acid transport / brown fat cell differentiation / cytoskeletal protein binding / cholesterol homeostasis / negative regulation of cell population proliferation / extracellular space / extracellular exosome / nucleus / cytosolSimilarity search - Function Cytosolic fatty-acid binding proteins signature. / Intracellular lipid binding protein / Cytosolic fatty-acid binding / Calycin beta-barrel core domain / Lipocalin / cytosolic fatty-acid binding protein family / Lipocalin/cytosolic fatty-acid binding domain / Calycin / Lipocalin / Beta Barrel / Mainly BetaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.37 Å |
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Authors | Sugiyama, S. / Matsuoka, S. / Mizohata, E. / Matsuoka, D. / Murakami, S. / Inoue, T. / Murata, M. |
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Funding support | Japan, 1items Organization | Grant number | Country |
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JSPS KAKENHI | 25286051 | Japan |
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Citation | Journal: J.Phys.Chem.B / Year: 2015 Title: Molecular Dynamics Simulations of Heart-type Fatty Acid Binding Protein in Apo and Holo Forms, and Hydration Structure Analyses in the Binding Cavity Authors: Matsuoka, D. / Sugiyama, S. / Murata, M. / Matsuoka, S. |
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History | Deposition | Sep 3, 2014 | Deposition site: RCSB / Processing site: PDBJ |
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Revision 1.0 | Jan 28, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jan 29, 2020 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Source and taxonomy Category: citation / diffrn_source ...citation / diffrn_source / entity_src_gen / pdbx_database_status / pdbx_struct_oper_list Item: _citation.journal_id_CSD / _diffrn_source.pdbx_synchrotron_site ..._citation.journal_id_CSD / _diffrn_source.pdbx_synchrotron_site / _entity_src_gen.pdbx_alt_source_flag / _pdbx_database_status.pdb_format_compatible / _pdbx_struct_oper_list.symmetry_operation |
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Revision 1.2 | Mar 20, 2024 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / refine_hist Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _refine_hist.number_atoms_solvent / _refine_hist.number_atoms_total / _refine_hist.pdbx_number_atoms_ligand / _refine_hist.pdbx_number_atoms_nucleic_acid / _refine_hist.pdbx_number_atoms_protein |
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