+Open data
-Basic information
Entry | Database: PDB / ID: 6aq1 | ||||||
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Title | The crystal structure of human FABP3 | ||||||
Components | Fatty acid-binding protein, heart | ||||||
Keywords | TRANSPORT PROTEIN / human / FABP3 | ||||||
Function / homology | Function and homology information positive regulation of long-chain fatty acid import into cell / regulation of phosphatidylcholine biosynthetic process / regulation of fatty acid oxidation / positive regulation of phospholipid biosynthetic process / intracellular lipid transport / oleic acid binding / phospholipid homeostasis / long-chain fatty acid binding / Triglyceride catabolism / long-chain fatty acid transport ...positive regulation of long-chain fatty acid import into cell / regulation of phosphatidylcholine biosynthetic process / regulation of fatty acid oxidation / positive regulation of phospholipid biosynthetic process / intracellular lipid transport / oleic acid binding / phospholipid homeostasis / long-chain fatty acid binding / Triglyceride catabolism / long-chain fatty acid transport / brown fat cell differentiation / cytoskeletal protein binding / cholesterol homeostasis / negative regulation of cell population proliferation / extracellular space / extracellular exosome / nucleus / cytosol Similarity search - Function | ||||||
Biological species | Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.40000091001 Å | ||||||
Authors | Hsu, H.C. / Li, H. | ||||||
Funding support | United States, 1items
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Citation | Journal: Eur J Med Chem / Year: 2018 Title: SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Authors: Yan, S. / Elmes, M.W. / Tong, S. / Hu, K. / Awwa, M. / Teng, G.Y.H. / Jing, Y. / Freitag, M. / Gan, Q. / Clement, T. / Wei, L. / Sweeney, J.M. / Joseph, O.M. / Che, J. / Carbonetti, G.S. / ...Authors: Yan, S. / Elmes, M.W. / Tong, S. / Hu, K. / Awwa, M. / Teng, G.Y.H. / Jing, Y. / Freitag, M. / Gan, Q. / Clement, T. / Wei, L. / Sweeney, J.M. / Joseph, O.M. / Che, J. / Carbonetti, G.S. / Wang, L. / Bogdan, D.M. / Falcone, J. / Smietalo, N. / Zhou, Y. / Ralph, B. / Hsu, H.C. / Li, H. / Rizzo, R.C. / Deutsch, D.G. / Kaczocha, M. / Ojima, I. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 6aq1.cif.gz | 98.6 KB | Display | PDBx/mmCIF format |
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PDB format | pdb6aq1.ent.gz | 59.6 KB | Display | PDB format |
PDBx/mmJSON format | 6aq1.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 6aq1_validation.pdf.gz | 958.3 KB | Display | wwPDB validaton report |
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Full document | 6aq1_full_validation.pdf.gz | 948.4 KB | Display | |
Data in XML | 6aq1_validation.xml.gz | 16.9 KB | Display | |
Data in CIF | 6aq1_validation.cif.gz | 24.8 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/aq/6aq1 ftp://data.pdbj.org/pub/pdb/validation_reports/aq/6aq1 | HTTPS FTP |
-Related structure data
Related structure data | 1hmsS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1
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