Entry Database : PDB / ID : 4tz7 Structure visualization Downloads & linksTitle Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish ComponentsPhosphatidylinositol-4-phosphate 5-kinase, type I, alpha Details Keywords TRANSFERASE / KinaseFunction / homology Function and homology informationFunction Domain/homology Component
Synthesis of PIPs at the plasma membrane / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / 1-phosphatidylinositol-4-phosphate 5-kinase / lipid kinase activity / 1-phosphatidylinositol-4-phosphate 5-kinase activity / phosphatidylinositol phosphate biosynthetic process / phosphorylation / ATP binding / metal ion binding / plasma membrane Similarity search - Function Phosphatidylinositol Phosphate Kinase II Beta / Phosphatidylinositol Phosphate Kinase II Beta / Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 / 2-Layer Sandwich / Phosphatidylinositol-4-phosphate 5-kinase / : / Phosphatidylinositol-4-phosphate 5-kinase, core / Phosphatidylinositol-4-phosphate 5-kinase, N-terminal / Phosphatidylinositol-4-phosphate 5-Kinase / Phosphatidylinositol phosphate kinase (PIPK) domain profile. ... Phosphatidylinositol Phosphate Kinase II Beta / Phosphatidylinositol Phosphate Kinase II Beta / Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2 / 2-Layer Sandwich / Phosphatidylinositol-4-phosphate 5-kinase / : / Phosphatidylinositol-4-phosphate 5-kinase, core / Phosphatidylinositol-4-phosphate 5-kinase, N-terminal / Phosphatidylinositol-4-phosphate 5-Kinase / Phosphatidylinositol phosphate kinase (PIPK) domain profile. / Phosphatidylinositol phosphate kinases / 2-Layer Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Danio rerio (zebrafish)Method X-RAY DIFFRACTION / SYNCHROTRON / Resolution : 3.31 Å DetailsAuthors Hu, J. / Qin, Y. / Wang, J. / Li, L. / Wu, D. / Ha, Y. CitationJournal : Nat Commun / Year : 2015Title : Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.Authors : Hu, J. / Yuan, Q. / Kang, X. / Qin, Y. / Li, L. / Ha, Y. / Wu, D. History Deposition Jul 9, 2014 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Sep 2, 2015 Provider : repository / Type : Initial releaseRevision 1.1 Sep 23, 2015 Group : Database references / Structure summaryRevision 1.2 Dec 27, 2023 Group : Data collection / Database references / Derived calculationsCategory : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_oper_list Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_oper_list.symmetry_operation
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