登録情報 | データベース: PDB / ID: 4tgf |
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タイトル | SOLUTION STRUCTURES OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA DERIVED FROM 1*H NMR DATA |
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要素 | DES-VAL-1,VAL-2,TRANSFORMING GROWTH FACTOR, ALPHA |
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キーワード | GROWTH FACTOR |
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機能・相同性 | 機能・相同性情報
hepatocyte proliferation / Cargo concentration in the ER / COPII-mediated vesicle transport / Inhibition of Signaling by Overexpressed EGFR / EGFR interacts with phospholipase C-gamma / ERBB2-EGFR signaling pathway / epidermal growth factor receptor binding / Signaling by EGFR / transmembrane receptor protein tyrosine kinase activator activity / positive regulation of cell division ...hepatocyte proliferation / Cargo concentration in the ER / COPII-mediated vesicle transport / Inhibition of Signaling by Overexpressed EGFR / EGFR interacts with phospholipase C-gamma / ERBB2-EGFR signaling pathway / epidermal growth factor receptor binding / Signaling by EGFR / transmembrane receptor protein tyrosine kinase activator activity / positive regulation of cell division / Estrogen-dependent nuclear events downstream of ESR-membrane signaling / mammary gland alveolus development / GAB1 signalosome / GRB2 events in EGFR signaling / SHC1 events in EGFR signaling / TFAP2 (AP-2) family regulates transcription of growth factors and their receptors / endoplasmic reticulum-Golgi intermediate compartment membrane / positive regulation of mitotic nuclear division / positive regulation of epithelial cell proliferation / EGFR downregulation / growth factor activity / clathrin-coated endocytic vesicle membrane / ER to Golgi transport vesicle membrane / epidermal growth factor receptor signaling pathway / Constitutive Signaling by Aberrant PI3K in Cancer / positive regulation of peptidyl-tyrosine phosphorylation / Cargo recognition for clathrin-mediated endocytosis / PIP3 activates AKT signaling / Clathrin-mediated endocytosis / PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling / cytoplasmic vesicle / RAF/MAP kinase cascade / basolateral plasma membrane / angiogenesis / Estrogen-dependent gene expression / positive regulation of MAPK cascade / Extra-nuclear estrogen signaling / receptor ligand activity / intracellular signal transduction / positive regulation of cell population proliferation / endoplasmic reticulum membrane / perinuclear region of cytoplasm / cell surface / extracellular space / extracellular region / plasma membrane類似検索 - 分子機能 Laminin / Laminin / EGF-like domain profile. / EGF-like domain signature 2. / EGF-like domain signature 1. / EGF-like domain / Ribbon / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR |
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データ登録者 | Kline, T.P. / Brown, F.K. / Brown, S.C. / Jeffs, P.W. / Kopple, K.D. / Mueller, L. |
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引用 | |
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履歴 | 登録 | 1990年6月13日 | 処理サイト: BNL |
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改定 1.0 | 1991年10月15日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月25日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2017年11月29日 | Group: Derived calculations / Other カテゴリ: pdbx_database_status / pdbx_struct_assembly ...pdbx_database_status / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conf Item: _pdbx_database_status.process_site |
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