登録情報 | データベース: PDB / ID: 4q2v |
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タイトル | Crystal Structure of Ricin A chain complexed with Baicalin inhibitor |
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要素 | Ricin |
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キーワード | Hydrolase/Hydrolase inhibitor / mixed alpha/beta structure / ribosome-inactivating / baicalin complex / ribosome / Hydrolase-Hydrolase inhibitor complex |
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機能・相同性 | 機能・相同性情報
rRNA N-glycosylase / rRNA N-glycosylase activity / AMP binding / defense response / toxin activity / carbohydrate binding / killing of cells of another organism / negative regulation of translation類似検索 - 分子機能 Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. / Ricin-type beta-trefoil lectin domain / Ribosome-inactivating protein type 1/2 / Ribosome-inactivating protein / Ribosome-inactivating protein, subdomain 1 ...Ricin (A Subunit), domain 2 / Ricin (A Subunit), domain 2 / Ricin (A subunit); domain 1 / Ricin (A subunit), domain 1 / Ribosome-inactivating protein conserved site / Shiga/ricin ribosomal inactivating toxins active site signature. / Ricin-type beta-trefoil lectin domain / Ribosome-inactivating protein type 1/2 / Ribosome-inactivating protein / Ribosome-inactivating protein, subdomain 1 / Ribosome-inactivating protein, subdomain 2 / Ribosome-inactivating protein superfamily / Ribosome inactivating protein / Ricin-type beta-trefoil / Lectin domain of ricin B chain profile. / Ricin B, lectin domain / Ricin B-like lectins / Few Secondary Structures / Irregular / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Ricinus communis (トウゴマ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.198 Å |
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データ登録者 | Deng, X. / Li, X. / Dong, J. / Chen, Y. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2015 タイトル: Baicalin inhibits the lethality of ricin in mice by inducing protein oligomerization. 著者: Dong, J. / Zhang, Y. / Chen, Y. / Niu, X. / Zhang, Y. / Li, R. / Yang, C. / Wang, Q. / Li, X. / Deng, X. |
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履歴 | 登録 | 2014年4月10日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2015年4月15日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2020年1月1日 | Group: Database references / カテゴリ: citation / struct_ref_seq_dif Item: _citation.journal_volume / _citation.page_first ..._citation.journal_volume / _citation.page_first / _citation.page_last / _citation.pdbx_database_id_PubMed / _citation.title / _struct_ref_seq_dif.details |
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改定 1.2 | 2023年11月8日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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