登録情報 | データベース: PDB / ID: 4pk2 |
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タイトル | tubulin acetyltransferase complex with bisubstrate analog |
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要素 | - ACETYL-SER-(N-PROPANOYL-LYS)-ASP--THR-NH2 PEPTIDE
- Alpha-tubulin N-acetyltransferase 1
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キーワード | Transferase/Peptide / tubulin / acetyltransferase / bisubstrate / coA / Transferase-Peptide complex |
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機能・相同性 | 機能・相同性情報
alpha-tubulin N-acetyltransferase / tubulin N-acetyltransferase activity / alpha-tubulin acetylation / microtubule bundle / Cilium Assembly / lysine N-acetyltransferase activity, acting on acetyl phosphate as donor / NLRP3 inflammasome complex assembly / dentate gyrus development / regulation of fat cell differentiation / positive regulation of NLRP3 inflammasome complex assembly ...alpha-tubulin N-acetyltransferase / tubulin N-acetyltransferase activity / alpha-tubulin acetylation / microtubule bundle / Cilium Assembly / lysine N-acetyltransferase activity, acting on acetyl phosphate as donor / NLRP3 inflammasome complex assembly / dentate gyrus development / regulation of fat cell differentiation / positive regulation of NLRP3 inflammasome complex assembly / response to pain / cilium assembly / neuron development / regulation of microtubule cytoskeleton organization / response to mechanical stimulus / clathrin-coated pit / mitotic spindle / microtubule cytoskeleton organization / spermatogenesis / microtubule / axon / focal adhesion / Golgi apparatus / cytosol類似検索 - 分子機能 Gcn5-related N-acetyltransferase (GNAT) domain, ATAT-type / Alpha-tubulin N-acetyltransferase / GNAT acetyltransferase, Mec-17 / Alpha-tubulin Gcn5-related N-acetyltransferase (GNAT) domain profile. / Gcn5-related N-acetyltransferase (GNAT) / Aminopeptidase / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 COENZYME A / Alpha-tubulin N-acetyltransferase 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) synthetic construct (人工物) |
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手法 | X線回折 / シンクロトロン / 解像度: 1.35 Å |
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データ登録者 | Szyk, A. / Roll-Mecak, A. |
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資金援助 | 米国, 1件 組織 | 認可番号 | 国 |
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National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS) | 1ZIANS003122-04 | 米国 |
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引用 | ジャーナル: Cell / 年: 2014 タイトル: Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase. 著者: Szyk, A. / Deaconescu, A.M. / Spector, J. / Goodman, B. / Valenstein, M.L. / Ziolkowska, N.E. / Kormendi, V. / Grigorieff, N. / Roll-Mecak, A. |
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履歴 | 登録 | 2014年5月13日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2014年8月13日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2015年2月25日 | Group: Other |
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改定 1.2 | 2017年9月20日 | Group: Advisory / Author supporting evidence ...Advisory / Author supporting evidence / Derived calculations / Other / Source and taxonomy カテゴリ: entity_src_gen / pdbx_audit_support ...entity_src_gen / pdbx_audit_support / pdbx_database_status / pdbx_entity_src_syn / pdbx_struct_oper_list / pdbx_validate_close_contact / pdbx_validate_symm_contact Item: _entity_src_gen.pdbx_alt_source_flag / _pdbx_audit_support.funding_organization ..._entity_src_gen.pdbx_alt_source_flag / _pdbx_audit_support.funding_organization / _pdbx_database_status.pdb_format_compatible / _pdbx_entity_src_syn.pdbx_alt_source_flag / _pdbx_struct_oper_list.symmetry_operation / _pdbx_validate_symm_contact.auth_seq_id_1 / _pdbx_validate_symm_contact.auth_seq_id_2 / _pdbx_validate_symm_contact.dist / _pdbx_validate_symm_contact.site_symmetry_2 |
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改定 1.3 | 2019年12月18日 | Group: Author supporting evidence / カテゴリ: pdbx_audit_support / Item: _pdbx_audit_support.funding_organization |
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改定 1.4 | 2023年12月27日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / refine_hist Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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