Entry | Database: PDB / ID: 4mgr |
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Title | The crystal structure of Bacillus subtilis GabR, an autorepressor and PLP- and GABA-dependent transcriptional activator of gabT |
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Components | HTH-type transcriptional regulatory protein GabR |
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Keywords | TRANSCRIPTION REGULATOR / Winged Helix Turn Helix / type-I aminotransferase / PLP Binding / DNA Binding |
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Function / homology | Function and homology information
transaminase activity / biosynthetic process / pyridoxal phosphate binding / DNA-binding transcription factor activity / DNA bindingSimilarity search - Function GntR-type HTH domain profile. / helix_turn_helix gluconate operon transcriptional repressor / Transcription regulator HTH, GntR / Bacterial regulatory proteins, gntR family / Aminotransferase, class I/classII / Aminotransferase class I and II / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Pyridoxal phosphate-dependent transferase, major domain ...GntR-type HTH domain profile. / helix_turn_helix gluconate operon transcriptional repressor / Transcription regulator HTH, GntR / Bacterial regulatory proteins, gntR family / Aminotransferase, class I/classII / Aminotransferase class I and II / Aspartate Aminotransferase; domain 2 / Type I PLP-dependent aspartate aminotransferase-like (Major domain) / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Pyridoxal phosphate-dependent transferase, major domain / Pyridoxal phosphate-dependent transferase / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Orthogonal Bundle / 3-Layer(aba) Sandwich / Mainly Alpha / Alpha BetaSimilarity search - Domain/homology |
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Biological species | Bacillus subtilis (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.55 Å |
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Authors | Wu, R. / Edayathumangalam, R. / Garcia, R. / Wang, Y. / Wang, W. / Kreinbring, C.A. / Bach, A. / Liao, J. / Stone, T. / Terwilliger, T. ...Wu, R. / Edayathumangalam, R. / Garcia, R. / Wang, Y. / Wang, W. / Kreinbring, C.A. / Bach, A. / Liao, J. / Stone, T. / Terwilliger, T. / Hoang, Q.Q. / Belitsky, B.R. / Petsko, G.A. / Ringe, D. / Liu, D. |
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Citation | Journal: Proc.Natl.Acad.Sci.USA / Year: 2013 Title: Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Authors: Edayathumangalam, R. / Wu, R. / Garcia, R. / Wang, Y. / Wang, W. / Kreinbring, C.A. / Bach, A. / Liao, J. / Stone, T.A. / Terwilliger, T.C. / Hoang, Q.Q. / Belitsky, B.R. / Petsko, G.A. / Ringe, D. / Liu, D. |
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History | Deposition | Aug 28, 2013 | Deposition site: RCSB / Processing site: RCSB |
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Revision 1.0 | Oct 30, 2013 | Provider: repository / Type: Initial release |
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Revision 1.1 | Feb 5, 2014 | Group: Database references |
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Revision 1.2 | Feb 28, 2024 | Group: Data collection / Database references / Derived calculations Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_struct_conn_angle / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_struct_conn_angle.ptnr1_auth_asym_id / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr2_auth_asym_id / _pdbx_struct_conn_angle.ptnr2_label_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_asym_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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