登録情報 データベース : PDB / ID : 4jvu 構造の表示 ダウンロードとリンクタイトル IgM C2-domain from mouse 要素Ig mu chain C region membrane-bound form 詳細 キーワード PROTEIN BINDING / Immunoglobulin M / antibody / oligomerization / Immunoglobulin fold / Receptor機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
CD22 mediated BCR regulation / : / IgM B cell receptor complex / pentameric IgM immunoglobulin complex / B cell receptor complex / Cell surface interactions at the vascular wall / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / pre-B cell allelic exclusion / positive regulation of B cell activation / B cell affinity maturation ... CD22 mediated BCR regulation / : / IgM B cell receptor complex / pentameric IgM immunoglobulin complex / B cell receptor complex / Cell surface interactions at the vascular wall / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / pre-B cell allelic exclusion / positive regulation of B cell activation / B cell affinity maturation / humoral immune response mediated by circulating immunoglobulin / early endosome to late endosome transport / phagocytosis, recognition / regulation of cell morphogenesis / regulation of immunoglobulin production / phagocytosis, engulfment / B cell activation / B cell proliferation / antigen processing and presentation / positive regulation of endocytosis / immunoglobulin mediated immune response / positive regulation of B cell proliferation / immunoglobulin complex, circulating / immunoglobulin receptor binding / complement activation, classical pathway / antigen binding / B cell receptor signaling pathway / transmembrane signaling receptor activity / positive regulation of peptidyl-tyrosine phosphorylation / positive regulation of immune response / MAPK cascade / antibacterial humoral response / defense response to Gram-negative bacterium / positive regulation of MAPK cascade / membrane => GO:0016020 / blood microparticle / defense response to bacterium / external side of plasma membrane / innate immune response / perinuclear region of cytoplasm / cell surface / extracellular space / extracellular exosome / identical protein binding / membrane / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能 Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold ... Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性 Immunoglobulin heavy constant mu / Immunoglobulin heavy constant mu 類似検索 - 構成要素生物種 Mus musculus (ハツカネズミ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.3 Å 詳細データ登録者 Mueller, R. / Graewert, A.M. / Kern, T. / Madl, T. / Peschek, J. / Sattler, M. / Groll, M. / Buchner, J. 引用ジャーナル : Proc.Natl.Acad.Sci.USA / 年 : 2013タイトル : High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation.著者 : Muller, R. / Grawert, M.A. / Kern, T. / Madl, T. / Peschek, J. / Sattler, M. / Groll, M. / Buchner, J. 履歴 登録 2013年3月26日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2013年6月12日 Provider : repository / タイプ : Initial release改定 1.1 2013年7月3日 Group : Database references改定 1.2 2023年9月20日 Group : Data collection / Database references / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details
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