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Structure paper

TitleHigh Resolution Structures of the Igm Fc Domains Reveal Principles of its Hexamer Formation
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 10183-, Year 2013
Publish dateSep 12, 2012 (structure data deposition date)
AuthorsMueller, R. / Graewert, M.A. / Kern, T. / Madl, T. / Peschek, J. / Sattler, M. / Groll, M. / Buchner, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:23733956
MethodsNMR (solution) / X-ray diffraction
Resolution1.3 - 2 Å
Structure data

PDB-4ba8:
High resolution NMR structure of the C mu3 domain from IgM
Method: SOLUTION NMR

PDB-4jvu:
IgM C2-domain from mouse
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-4jvw:
IgM C4-domain from mouse
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / IMMUNOGLOBULIN CONSTANT REGION / PROTEIN BINDING / Immunoglobulin M / antibody / oligomerization / Immunoglobulin fold / Receptor

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