regulation of oogenesis / Regulation of TP53 Expression / Regulation of TP53 Activity through Acetylation / Regulation of TP53 Activity through Association with Co-factors / Regulation of TP53 Activity through Methylation / RUNX3 regulates CDKN1A transcription / Regulation of TP53 Activity through Phosphorylation / PKR-mediated signaling / Autodegradation of the E3 ubiquitin ligase COP1 / G2/M Checkpoints ...regulation of oogenesis / Regulation of TP53 Expression / Regulation of TP53 Activity through Acetylation / Regulation of TP53 Activity through Association with Co-factors / Regulation of TP53 Activity through Methylation / RUNX3 regulates CDKN1A transcription / Regulation of TP53 Activity through Phosphorylation / PKR-mediated signaling / Autodegradation of the E3 ubiquitin ligase COP1 / G2/M Checkpoints / Ovarian tumor domain proteases / epithelium development / Ub-specific processing proteases / Oxidative Stress Induced Senescence / Oncogene Induced Senescence / Regulation of TP53 Degradation / Stabilization of p53 / The role of GTSE1 in G2/M progression after G2 checkpoint / intestinal epithelial structure maintenance / programmed cell death involved in cell development / hematopoietic stem cell homeostasis / epidermis morphogenesis / apoptotic process involved in blood vessel morphogenesis / negative regulation of cell division / retrotransposon silencing / regulation of double-strand break repair / apoptotic process involved in development / response to methylmercury / definitive hemopoiesis / regulation of intrinsic apoptotic signaling pathway by p53 class mediator / DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator / hematopoietic stem cell proliferation / erythrocyte maturation / negative regulation of cell cycle / response to X-ray / intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator / anatomical structure morphogenesis / erythrocyte development / positive regulation of cell cycle / response to UV / intrinsic apoptotic signaling pathway / negative regulation of angiogenesis / transforming growth factor beta receptor signaling pathway / DNA damage checkpoint signaling / promoter-specific chromatin binding / protein tetramerization / regulation of protein stability / autophagy / cellular senescence / positive regulation of neuron apoptotic process / regulation of cell population proliferation / cellular response to hypoxia / spermatogenesis / sequence-specific DNA binding / DNA-binding transcription factor activity, RNA polymerase II-specific / cell cycle / positive regulation of apoptotic process / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / apoptotic process / DNA damage response / chromatin / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / mitochondrion / identical protein binding / nucleus / metal ion binding / cytoplasm Similarity search - Function
Mass: 18.015 Da / Num. of mol.: 140 / Source method: isolated from a natural source / Formula: H2O
Sequence details
ADDITIONAL GGS SEQUENCE AT THE N TERMINUS AS A RESULT OF CLONING STRATEGY
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2 Å3/Da / Density % sol: 38 % / Description: NONE
Crystal grow
Temperature: 293 K / Method: vapor diffusion, sitting drop / pH: 5 Details: SITTING DROP VAPOR DIFFUSION AT 20 DEGREE C; PROTEIN SOLUTION: 17 MG/ML IN 20 MM TRIS PH 7.5, 50 MM NACL, 5 MM DTT; CRYSTALLIZATION BUFFER: 1.8 M SODIUM/POTASSIUM PHOSPHATE, PH 5.0.