Entry Database : PDB / ID : 4cnu Structure visualization Downloads & linksTitle CRYSTAL STRUCTURE OF WT HUMAN CRMP-4 from lattice translocation ComponentsDIHYDROPYRIMIDINASE-LIKE 3 Details Keywords SIGNALING PROTEIN / NEUROGENESIS / AXONAL OUTGROWTH / DEVELOPMENTAL PROTEINFunction / homology Function and homology informationFunction Domain/homology Component
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides / filamin binding / chondroitin sulfate binding / actin crosslink formation / exocytic vesicle / CRMPs in Sema3A signaling / positive regulation of filopodium assembly / cellular response to cytokine stimulus / filamentous actin / actin filament bundle assembly ... hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides / filamin binding / chondroitin sulfate binding / actin crosslink formation / exocytic vesicle / CRMPs in Sema3A signaling / positive regulation of filopodium assembly / cellular response to cytokine stimulus / filamentous actin / actin filament bundle assembly / response to axon injury / neuron development / negative regulation of cell migration / positive regulation of neuron projection development / SH3 domain binding / lamellipodium / negative regulation of neuron projection development / cell body / growth cone / synapse / extracellular space / identical protein binding / cytosol Similarity search - Function Hydantoinase/dihydropyrimidinase / Urease, subunit C; domain 1 / Urease, subunit C, domain 1 / Amidohydrolase family / Metal-dependent hydrolase, composite domain superfamily / Amidohydrolase-related / Metal-dependent hydrolases / Metal-dependent hydrolase / Roll / TIM Barrel ... Hydantoinase/dihydropyrimidinase / Urease, subunit C; domain 1 / Urease, subunit C, domain 1 / Amidohydrolase family / Metal-dependent hydrolase, composite domain superfamily / Amidohydrolase-related / Metal-dependent hydrolases / Metal-dependent hydrolase / Roll / TIM Barrel / Alpha-Beta Barrel / Mainly Beta / Alpha Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.8 Å DetailsAuthors Ponnusamy, R. / Lebedev, A. / Lohkamp, B. CitationJournal : Acta Crystallogr.,Sect.D / Year : 2014Title : Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation DisorderAuthors : Ponnusamy, R. / Lebedev, A. / Pahlow, S. / Lohkamp, B. History Deposition Jan 24, 2014 Deposition site : PDBE / Processing site : PDBERevision 1.0 Jun 18, 2014 Provider : repository / Type : Initial releaseRevision 1.1 Jan 17, 2018 Group : Data collection / Category : diffrn_source / Item : _diffrn_source.pdbx_synchrotron_siteRevision 1.2 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_ncs_dom_lim Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id
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