Entry Database : PDB / ID : 4bkn Structure visualization Downloads & linksTitle Human Dihydropyrimidinase-related protein 3 (DPYSL3) ComponentsDIHYDROPYRIMIDINASE-RELATED PROTEIN 3 Details Keywords HYDROLASE / AXON OUTGROWTH / HOMOTETRAMERFunction / homology Function and homology informationFunction Domain/homology Component
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides / chondroitin sulfate binding / filamin binding / actin crosslink formation / exocytic vesicle / CRMPs in Sema3A signaling / positive regulation of filopodium assembly / cellular response to cytokine stimulus / filamentous actin / actin filament bundle assembly ... hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides / chondroitin sulfate binding / filamin binding / actin crosslink formation / exocytic vesicle / CRMPs in Sema3A signaling / positive regulation of filopodium assembly / cellular response to cytokine stimulus / filamentous actin / actin filament bundle assembly / neuron development / response to axon injury / negative regulation of cell migration / positive regulation of neuron projection development / SH3 domain binding / negative regulation of neuron projection development / lamellipodium / cell body / growth cone / synapse / extracellular space / identical protein binding / cytosol Similarity search - Function Hydantoinase/dihydropyrimidinase / Urease, subunit C; domain 1 / Urease, subunit C, domain 1 / Amidohydrolase family / Metal-dependent hydrolase, composite domain superfamily / Amidohydrolase-related / Metal-dependent hydrolases / Metal-dependent hydrolase / Roll / TIM Barrel ... Hydantoinase/dihydropyrimidinase / Urease, subunit C; domain 1 / Urease, subunit C, domain 1 / Amidohydrolase family / Metal-dependent hydrolase, composite domain superfamily / Amidohydrolase-related / Metal-dependent hydrolases / Metal-dependent hydrolase / Roll / TIM Barrel / Alpha-Beta Barrel / Mainly Beta / Alpha Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.1 Å DetailsAuthors Mathea, S. / Elkins, J.M. / Alegre-Abarrategui, J. / Shrestha, L. / Burgess-Brown, N. / Puranik, S. / Coutandin, D. / Bradley, A. / Vollmar, M. / von Delft, F. ...Mathea, S. / Elkins, J.M. / Alegre-Abarrategui, J. / Shrestha, L. / Burgess-Brown, N. / Puranik, S. / Coutandin, D. / Bradley, A. / Vollmar, M. / von Delft, F. / Bountra, C. / Arrowsmith, C. / Edwards, A. / Knapp, S. CitationJournal : To be Published Title : Structure of Dpysl3Authors : Mathea, S. History Deposition Apr 26, 2013 Deposition site : PDBE / Processing site : PDBERevision 1.0 May 8, 2013 Provider : repository / Type : Initial releaseRevision 1.1 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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