登録情報 | データベース: PDB / ID: 4c6a |
---|
タイトル | High Resolution Structure of the Nucleoside diphosphate kinase |
---|
要素 | NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC |
---|
キーワード | TRANSFERASE / PHOSPHOTRANSFERASE |
---|
機能・相同性 | 機能・相同性情報
dGTP biosynthetic process from dGDP / Azathioprine ADME / Ribavirin ADME / asexual reproduction / Interconversion of nucleotide di- and triphosphates / Neutrophil degranulation / nucleoside triphosphate biosynthetic process / negative regulation of pinocytosis / nucleoside-diphosphate kinase / CTP biosynthetic process ...dGTP biosynthetic process from dGDP / Azathioprine ADME / Ribavirin ADME / asexual reproduction / Interconversion of nucleotide di- and triphosphates / Neutrophil degranulation / nucleoside triphosphate biosynthetic process / negative regulation of pinocytosis / nucleoside-diphosphate kinase / CTP biosynthetic process / UTP biosynthetic process / negative regulation of exocytosis / negative regulation of phagocytosis / GTP biosynthetic process / nucleoside diphosphate kinase activity / translational elongation / phagocytic vesicle / secretory granule / response to bacterium / actin cytoskeleton organization / cytoskeleton / ribosome / G protein-coupled receptor signaling pathway / phosphorylation / ATP binding / metal ion binding / plasma membrane / cytoplasm類似検索 - 分子機能 Nucleoside diphosphate kinase (NDPK)-like domain profile. / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase, active site / Nucleoside diphosphate kinase (NDPK) active site signature. / Nucleoside diphosphate kinase / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase / NDK / Nucleoside diphosphate kinase-like domain superfamily / Alpha-Beta Plaits ...Nucleoside diphosphate kinase (NDPK)-like domain profile. / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase, active site / Nucleoside diphosphate kinase (NDPK) active site signature. / Nucleoside diphosphate kinase / Nucleoside diphosphate kinase-like domain / Nucleoside diphosphate kinase / NDK / Nucleoside diphosphate kinase-like domain superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 DI(HYDROXYETHYL)ETHER / Nucleoside diphosphate kinase, cytosolic類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_eukaryote.gif) DICTYOSTELIUM DISCOIDEUM (キイロタマホコリカビ) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.25 Å |
---|
データ登録者 | Priet, S. / Ferron, F. / Alvarez, K. / Verron, M. / Canard, B. |
---|
引用 | ジャーナル: Antiviral Res. / 年: 2015 タイトル: Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity. 著者: Priet, S. / Roux, L. / Saez-Ayala, M. / Ferron, F. / Canard, B. / Alvarez, K. |
---|
履歴 | 登録 | 2013年9月18日 | 登録サイト: PDBE / 処理サイト: PDBE |
---|
改定 1.0 | 2013年11月20日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2015年3月25日 | Group: Database references |
---|
改定 1.2 | 2015年4月22日 | Group: Database references |
---|
改定 1.3 | 2023年12月20日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_special_symmetry / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
|
---|