- PDB-4a3n: Crystal Structure of HMG-BOX of Human SOX17 -
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Basic information
Entry
Database: PDB / ID: 4a3n
Title
Crystal Structure of HMG-BOX of Human SOX17
Components
TRANSCRIPTION FACTOR SOX-17
Keywords
TRANSCRIPTION
Function / homology
Function and homology information
cardiogenic plate morphogenesis / endodermal cell fate determination / regulation of cardiac cell fate specification / stem cell fate specification / endocardium formation / common bile duct development / endodermal digestive tract morphogenesis / ureter development / gallbladder development / inner cell mass cellular morphogenesis ...cardiogenic plate morphogenesis / endodermal cell fate determination / regulation of cardiac cell fate specification / stem cell fate specification / endocardium formation / common bile duct development / endodermal digestive tract morphogenesis / ureter development / gallbladder development / inner cell mass cellular morphogenesis / heart formation / cardiac cell fate determination / endodermal cell fate specification / regulation of stem cell division / cell migration involved in gastrulation / endoderm formation / Specification of primordial germ cells / rostrocaudal neural tube patterning / endocardial cell differentiation / positive regulation of endodermal cell differentiation / positive regulation of stem cell differentiation / embryonic foregut morphogenesis / regulation of stem cell proliferation / Formation of definitive endoderm / signal transduction involved in regulation of gene expression / metanephros development / embryonic heart tube development / embryonic heart tube morphogenesis / heart looping / outflow tract morphogenesis / regulation of embryonic development / vasculogenesis / cellular response to leukemia inhibitory factor / Deactivation of the beta-catenin transactivating complex / protein destabilization / negative regulation of canonical Wnt signaling pathway / negative regulation of cell growth / beta-catenin binding / Wnt signaling pathway / positive regulation of protein catabolic process / heart development / gene expression / spermatogenesis / DNA-binding transcription activator activity, RNA polymerase II-specific / angiogenesis / RNA polymerase II-specific DNA-binding transcription factor binding / transcription regulator complex / protein stabilization / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / positive regulation of gene expression / regulation of DNA-templated transcription / chromatin / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / nucleoplasm / nucleus Similarity search - Function
Sox, C-terminal / Sox 7/17/18, central domain / Sox 17/18 central domain / Sox C-terminal domain profile. / High mobility group box domain / DNA Binding (I), subunit A / HMG (high mobility group) box / HMG boxes A and B DNA-binding domains profile. / high mobility group / High mobility group box domain ...Sox, C-terminal / Sox 7/17/18, central domain / Sox 17/18 central domain / Sox C-terminal domain profile. / High mobility group box domain / DNA Binding (I), subunit A / HMG (high mobility group) box / HMG boxes A and B DNA-binding domains profile. / high mobility group / High mobility group box domain / High mobility group box domain superfamily / Orthogonal Bundle / Mainly Alpha Similarity search - Domain/homology
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