Entry Database : PDB / ID : 3zj7 Structure visualization Downloads & linksTitle Crystal structure of strictosidine glucosidase in complex with inhibitor-1 ComponentsSTRICTOSIDINE-O-BETA-D-GLUCOSIDASE Details Keywords HYDROLASE / ALKALOID / INHIBITOR / AJMALINEFunction / homology Function and homology informationFunction Domain/homology Component
3alpha(S)-strictosidine beta-glucosidase / strictosidine beta-glucosidase activity / alkaloid biosynthetic process / carbohydrate metabolic process Similarity search - Function Glycosyl hydrolases family 1, N-terminal conserved site / Glycosyl hydrolases family 1 N-terminal signature. / Glycosyl hydrolase family 1 / Glycoside hydrolase family 1 / Glycosidases / Glycoside hydrolase superfamily / TIM Barrel / Alpha-Beta Barrel / Alpha Beta Similarity search - Domain/homologyBiological species RAUVOLFIA SERPENTINA (serpentwood)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.5 Å DetailsAuthors Xia, L. / Lin, H. / Panjikar, S. / Ruppert, M. / Castiglia, A. / Rajendran, C. / Wang, M. / Schuebel, H. / Warzecha, H. / Jaeger, V. / Stoeckigt, J. CitationJournal : J.Enzyme.Inhib.Med.Chem. / Year : 2015Title : Ligand Structures of Synthetic Deoxa-Pyranosylamines with Raucaffricine and Strictosidine Glucosidases Provide Structural Insights Into Their Binding and Inhibitory Behaviours.Authors : Xia, L. / Lin, H. / Staniek, A. / Panjikar, S. / Ruppert, M. / Hilgers, P. / Williardt, J. / Rajendran, C. / Wang, M. / Warzecha, H. / Jager, V. / Stockigt, J. History Deposition Jan 17, 2013 Deposition site : PDBE / Processing site : PDBERevision 1.0 Feb 5, 2014 Provider : repository / Type : Initial releaseRevision 1.1 Feb 11, 2015 Group : Database referencesRevision 1.2 Jul 22, 2015 Group : Database referencesRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Show all Show less Remark 700 SHEET DETERMINATION METHOD: DSSP THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS BELOW ... SHEET DETERMINATION METHOD: DSSP THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "BA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL.