Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
要素
Non-capsid protein NS-1
キーワード
REPLICATION / Nuclease activity / Single and double stranded DNA binding / nicking protein
機能・相同性
機能・相同性情報
rolling hairpin viral DNA replication / symbiont-mediated arrest of host cell cycle during G2/M transition / symbiont-mediated perturbation of host transcription / symbiont-mediated perturbation of host apoptosis / 加水分解酵素; エステル加水分解酵素; 5'-リン酸モノエステル産生エンドデオキシリボヌクレアーゼ / symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint / helicase activity / DNA replication / DNA helicase / endonuclease activity ...rolling hairpin viral DNA replication / symbiont-mediated arrest of host cell cycle during G2/M transition / symbiont-mediated perturbation of host transcription / symbiont-mediated perturbation of host apoptosis / 加水分解酵素; エステル加水分解酵素; 5'-リン酸モノエステル産生エンドデオキシリボヌクレアーゼ / symbiont-mediated perturbation of host cell cycle G1/S transition checkpoint / helicase activity / DNA replication / DNA helicase / endonuclease activity / host cell nucleus / ATP hydrolysis activity / DNA binding / ATP binding / metal ion binding 類似検索 - 分子機能
Parvovirus non-structural protein 1, N-terminal / Parvovirus non-structural protein 1, C-terminal / Parvovirus non-structural protein 1, C-terminal / Parvovirus non-structural protein 1 / : / Parvovirus (PV) NS1 nuclease (NS1-Nuc) domain profile. / Parvovirus non-structural protein 1, helicase domain / Parvovirus non-structural protein NS1 / Helicase, superfamily 3, DNA virus / Superfamily 3 helicase of DNA viruses domain profile. / P-loop containing nucleoside triphosphate hydrolase 類似検索 - ドメイン・相同性
NICKEL (II) ION / Initiator protein NS1 類似検索 - 構成要素