登録情報 | データベース: PDB / ID: 3tdh |
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タイトル | Structure of the regulatory fragment of sccharomyces cerevisiae AMPK in complex with AMP |
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要素 | - Carbon catabolite-derepressing protein kinase
- Nuclear protein SNF4
- SNF1 protein kinase subunit beta-2
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キーワード | TRANSFERASE / CBS domain / Nucleotide binding / cytosol |
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機能・相同性 | 機能・相同性情報
fungal-type cell wall assembly / positive regulation of pseudohyphal growth / positive regulation of filamentous growth of a population of unicellular organisms in response to starvation / AMPK inhibits chREBP transcriptional activation activity / Energy dependent regulation of mTOR by LKB1-AMPK / single-species surface biofilm formation / regulation of cellular response to glucose starvation / regulation of invasive growth in response to glucose limitation / cellular bud neck septin ring / Carnitine metabolism ...fungal-type cell wall assembly / positive regulation of pseudohyphal growth / positive regulation of filamentous growth of a population of unicellular organisms in response to starvation / AMPK inhibits chREBP transcriptional activation activity / Energy dependent regulation of mTOR by LKB1-AMPK / single-species surface biofilm formation / regulation of cellular response to glucose starvation / regulation of invasive growth in response to glucose limitation / cellular bud neck septin ring / Carnitine metabolism / invasive growth in response to glucose limitation / Macroautophagy / peroxisome organization / filamentous growth / nucleotide-activated protein kinase complex / protein kinase regulator activity / enzyme-substrate adaptor activity / vacuolar membrane / AMP-activated protein kinase activity / nuclear envelope lumen / AMP binding / establishment of mitotic spindle orientation / positive regulation of macroautophagy / response to unfolded protein / regulation of protein-containing complex assembly / cellular response to glucose starvation / positive regulation of gluconeogenesis / response to endoplasmic reticulum stress / protein serine/threonine kinase activator activity / guanyl-nucleotide exchange factor activity / molecular function activator activity / autophagy / nuclear membrane / negative regulation of translation / non-specific serine/threonine protein kinase / protein kinase activity / intracellular signal transduction / phosphorylation / protein serine kinase activity / protein serine/threonine kinase activity / regulation of transcription by RNA polymerase II / protein kinase binding / signal transduction / mitochondrion / ATP binding / identical protein binding / nucleus / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 N-terminal domain of TfIIb - #290 / Carbon catabolite-derepressing protein kinase, ubiquitin-associated domain / Ubiquitin associated domain (UBA) / Kinase associated domain 1, KA1 / Association with the SNF1 complex (ASC) domain / ASC domain superfamily / 5'-AMP-activated protein kinase beta subunit, interaction domain / 5'-AMP-activated protein kinase beta subunit, interation domain / AMPK, C-terminal adenylate sensor domain / Adenylate sensor of SNF1-like protein kinase ...N-terminal domain of TfIIb - #290 / Carbon catabolite-derepressing protein kinase, ubiquitin-associated domain / Ubiquitin associated domain (UBA) / Kinase associated domain 1, KA1 / Association with the SNF1 complex (ASC) domain / ASC domain superfamily / 5'-AMP-activated protein kinase beta subunit, interaction domain / 5'-AMP-activated protein kinase beta subunit, interation domain / AMPK, C-terminal adenylate sensor domain / Adenylate sensor of SNF1-like protein kinase / AMP-activated protein kinase, glycogen-binding domain / Glycogen recognition site of AMP-activated protein kinase / CBS-domain / CBS-domain / KA1 domain/Ssp2, C-terminal / TATA-Binding Protein / CBS domain superfamily / Domain in cystathionine beta-synthase and other proteins. / N-terminal domain of TfIIb / CBS domain / CBS domain / CBS domain profile. / Single Sheet / Immunoglobulin E-set / Serine/threonine-protein kinase, active site / Serine/Threonine protein kinases active-site signature. / Protein kinase domain / Serine/Threonine protein kinases, catalytic domain / Roll / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Immunoglobulin-like fold / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Mainly Beta / Alpha Beta類似検索 - ドメイン・相同性 ADENOSINE MONOPHOSPHATE / Carbon catabolite-derepressing protein kinase / 5'-AMP-activated protein kinase subunit gamma / SNF1 protein kinase subunit beta-2類似検索 - 構成要素 |
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生物種 | ![](img/tx_yeast.gif) Saccharomyces cerevisiae (パン酵母) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.3 Å |
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データ登録者 | Mayer, F.V. / Heath, R. / Underwood, E. / Sanders, M.J. / Carmena, D. / McCartney, R. / Leiper, F.C. / Xiao, B. / Jing, C. / Walker, P.A. ...Mayer, F.V. / Heath, R. / Underwood, E. / Sanders, M.J. / Carmena, D. / McCartney, R. / Leiper, F.C. / Xiao, B. / Jing, C. / Walker, P.A. / Haire, L.F. / Ogrodowicz, R. / Martin, S.R. / Schmidt, M.C. / Gamblin, S.J. / Carling, D. |
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引用 | ジャーナル: Cell Metab / 年: 2011 タイトル: ADP Regulates SNF1, the Saccharomyces cerevisiae Homolog of AMP-Activated Protein Kinase. 著者: Mayer, F.V. / Heath, R. / Underwood, E. / Sanders, M.J. / Carmena, D. / McCartney, R.R. / Leiper, F.C. / Xiao, B. / Jing, C. / Walker, P.A. / Haire, L.F. / Ogrodowicz, R. / Martin, S.R. / ...著者: Mayer, F.V. / Heath, R. / Underwood, E. / Sanders, M.J. / Carmena, D. / McCartney, R.R. / Leiper, F.C. / Xiao, B. / Jing, C. / Walker, P.A. / Haire, L.F. / Ogrodowicz, R. / Martin, S.R. / Schmidt, M.C. / Gamblin, S.J. / Carling, D. |
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履歴 | 登録 | 2011年8月11日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2011年11月9日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年11月23日 | Group: Database references |
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改定 1.2 | 2024年2月28日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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