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データを開く
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基本情報
登録情報 | データベース: PDB / ID: 3sod | ||||||
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タイトル | CHANGES IN CRYSTALLOGRAPHIC STRUCTURE AND THERMOSTABILITY OF A CU,ZN SUPEROXIDE DISMUTASE MUTANT RESULTING FROM THE REMOVAL OF BURIED CYSTEINE | ||||||
![]() | COPPER,ZINC SUPEROXIDE DISMUTASE | ||||||
![]() | OXIDOREDUCTASE (SUPEROXIDE ACCEPTOR) | ||||||
機能・相同性 | ![]() Platelet degranulation / Detoxification of Reactive Oxygen Species / neurofilament cytoskeleton organization / protein phosphatase 2B binding / relaxation of vascular associated smooth muscle / response to superoxide / peripheral nervous system myelin maintenance / regulation of protein kinase activity / retina homeostasis / negative regulation of cholesterol biosynthetic process ...Platelet degranulation / Detoxification of Reactive Oxygen Species / neurofilament cytoskeleton organization / protein phosphatase 2B binding / relaxation of vascular associated smooth muscle / response to superoxide / peripheral nervous system myelin maintenance / regulation of protein kinase activity / retina homeostasis / negative regulation of cholesterol biosynthetic process / auditory receptor cell stereocilium organization / hydrogen peroxide biosynthetic process / myeloid cell homeostasis / positive regulation of catalytic activity / muscle cell cellular homeostasis / heart contraction / superoxide metabolic process / superoxide dismutase / transmission of nerve impulse / superoxide dismutase activity / regulation of multicellular organism growth / response to axon injury / ovarian follicle development / glutathione metabolic process / embryo implantation / : / dendrite cytoplasm / removal of superoxide radicals / reactive oxygen species metabolic process / regulation of mitochondrial membrane potential / positive regulation of cytokine production / locomotory behavior / sensory perception of sound / response to hydrogen peroxide / regulation of blood pressure / protein polyubiquitination / ubiquitin-protein transferase activity / peroxisome / protein-folding chaperone binding / response to heat / cytoplasmic vesicle / spermatogenesis / proteasome-mediated ubiquitin-dependent protein catabolic process / response to ethanol / intracellular iron ion homeostasis / negative regulation of neuron apoptotic process / positive regulation of MAPK cascade / copper ion binding / neuronal cell body / protein homodimerization activity / protein-containing complex / mitochondrion / zinc ion binding / nucleus / cytosol / cytoplasm 類似検索 - 分子機能 | ||||||
生物種 | ![]() ![]() | ||||||
手法 | ![]() | ||||||
![]() | Mcree, D.E. / Redford, S.M. / Getzoff, E.D. / Lepock, J.R. / Hallewell, R.A. / Tainer, J.A. | ||||||
![]() | ![]() タイトル: Changes in crystallographic structure and thermostability of a Cu,Zn superoxide dismutase mutant resulting from the removal of a buried cysteine. 著者: McRee, D.E. / Redford, S.M. / Getzoff, E.D. / Lepock, J.R. / Hallewell, R.A. / Tainer, J.A. | ||||||
履歴 |
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構造の表示
構造ビューア | 分子: ![]() ![]() |
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ダウンロードとリンク
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PDBx/mmCIF形式 | ![]() | 129.5 KB | 表示 | ![]() |
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PDB形式 | ![]() | 89.9 KB | 表示 | ![]() |
PDBx/mmJSON形式 | ![]() | ツリー表示 | ![]() | |
その他 | ![]() |
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アーカイブディレクトリ | ![]() ![]() | HTTPS FTP |
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-関連構造データ
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リンク
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集合体
登録構造単位 | ![]()
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単位格子 |
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非結晶学的対称性 (NCS) | NCS oper:
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要素
#1: タンパク質 | 分子量: 15567.311 Da / 分子数: 4 / 由来タイプ: 組換発現 / 由来: (組換発現) ![]() ![]() #2: 化合物 | ChemComp-CU / #3: 化合物 | ChemComp-ZN / |
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-実験情報
-実験
実験 | 手法: ![]() |
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試料調製
結晶 | マシュー密度: 2.33 Å3/Da / 溶媒含有率: 47.17 % | |||||||||||||||||||||||||
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結晶化 | *PLUS pH: 6.5 / 手法: unknown | |||||||||||||||||||||||||
溶液の組成 | *PLUS
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-データ収集
反射 | *PLUS 最高解像度: 2.1 Å / Num. obs: 28705 / % possible obs: 82 % / Num. measured all: 60573 / Rmerge(I) obs: 0.099 |
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反射 シェル | *PLUS 最高解像度: 2.1 Å / 最低解像度: 2.2 Å / % possible obs: 68 % |
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解析
ソフトウェア |
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精密化 | Rfactor Rwork: 0.19 / 最高解像度: 2.1 Å | ||||||||||||
精密化ステップ | サイクル: LAST / 最高解像度: 2.1 Å
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拘束条件 |
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ソフトウェア | *PLUS 名称: ![]() | ||||||||||||
精密化 | *PLUS 最低解像度: 8 Å / Num. reflection obs: 23715 / σ(I): 3 / Rfactor obs: 0.19 / Rfactor Rwork: 0.19 | ||||||||||||
溶媒の処理 | *PLUS | ||||||||||||
原子変位パラメータ | *PLUS |