登録情報 | データベース: PDB / ID: 3ozc |
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タイトル | Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase in complex with pCl-phenylthioDADMeImmA |
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要素 | S-methyl-5'-thioadenosine phosphorylase |
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キーワード | TRANSFERASE / 5'-methylthioadenosine / phosphorylase / MTAP / pCl-phenylthioDADMeImmA |
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機能・相同性 | 機能・相同性情報
Methionine salvage pathway / S-methyl-5'-thioadenosine phosphorylase / 1,4-alpha-oligoglucan phosphorylase activity / S-methyl-5-thioadenosine phosphorylase activity / L-methionine salvage from methylthioadenosine / nucleobase-containing compound metabolic process / purine ribonucleoside salvage / response to testosterone / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / methylation ...Methionine salvage pathway / S-methyl-5'-thioadenosine phosphorylase / 1,4-alpha-oligoglucan phosphorylase activity / S-methyl-5-thioadenosine phosphorylase activity / L-methionine salvage from methylthioadenosine / nucleobase-containing compound metabolic process / purine ribonucleoside salvage / response to testosterone / Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation / methylation / extracellular exosome / nucleoplasm / cytosol類似検索 - 分子機能 Methylthioadenosine phosphorylase (MTAP) / Purine phosphorylase, family 2, conserved site / Purine and other phosphorylases family 2 signature. / Nucleoside phosphorylase domain / Nucleoside phosphorylase domain / Phosphorylase superfamily / Nucleoside phosphorylase superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Chem-4CT / PHOSPHATE ION / S-methyl-5'-thioadenosine phosphorylase類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.93 Å |
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データ登録者 | Ho, M. / Guan, R. / Almo, S.C. / Schramm, V.L. |
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引用 | ジャーナル: to be published タイトル: Crystal Structure of human 5'-deoxy-5'-methyladenosine phosphorylase 著者: Ho, M. / Guan, R. / Almo, S.C. / Schramm, V.L. |
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履歴 | 登録 | 2010年9月24日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2011年9月28日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年11月8日 | Group: Refinement description / カテゴリ: software Item: _software.classification / _software.contact_author ..._software.classification / _software.contact_author / _software.contact_author_email / _software.date / _software.language / _software.location / _software.name / _software.type / _software.version |
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改定 1.2 | 2024年2月21日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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