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- PDB-3l89: Human Adenovirus type 21 knob in complex with domains SCR1 and SC... -
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Open data
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Basic information
Entry | Database: PDB / ID: 3l89 | ||||||
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Title | Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | ||||||
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![]() | VIRAL PROTEIN/PROTEIN BINDING / Adenovirus / Fiber Knob / Viral Protein / Membrane cofactor protein / MCP / virus receptor complex / SCR / Short consensus repeat / CCP / complement control protein / Complement pathway / Glycoprotein / Host-virus interaction / Immune response / Innate immunity / Sushi2 / VIRAL PROTEIN-PROTEIN BINDING complex | ||||||
Function / homology | ![]() sequestering of extracellular ligand from receptor / inner acrosomal membrane / regulation of Notch signaling pathway / negative regulation of complement activation, classical pathway / positive regulation of transforming growth factor beta production / T cell mediated immunity / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / adhesion receptor-mediated virion attachment to host cell / positive regulation of interleukin-10 production ...sequestering of extracellular ligand from receptor / inner acrosomal membrane / regulation of Notch signaling pathway / negative regulation of complement activation, classical pathway / positive regulation of transforming growth factor beta production / T cell mediated immunity / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / adhesion receptor-mediated virion attachment to host cell / positive regulation of interleukin-10 production / single fertilization / positive regulation of T cell proliferation / complement activation, classical pathway / Regulation of Complement cascade / viral capsid / virus receptor activity / signaling receptor activity / adaptive immune response / cell adhesion / cadherin binding / symbiont entry into host cell / negative regulation of gene expression / innate immune response / focal adhesion / positive regulation of gene expression / cell surface / extracellular space / extracellular exosome / plasma membrane Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Cupelli, K. / Stehle, T. | ||||||
![]() | ![]() Title: Structure of adenovirus type 21 knob in complex with CD46 reveals key differences in receptor contacts among species B adenoviruses. Authors: Cupelli, K. / Muller, S. / Persson, B.D. / Jost, M. / Arnberg, N. / Stehle, T. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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PDBx/mmCIF format | ![]() | 699.7 KB | Display | ![]() |
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PDB format | ![]() | 580.9 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 616.8 KB | Display | ![]() |
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Full document | ![]() | 705.6 KB | Display | |
Data in XML | ![]() | 128 KB | Display | |
Data in CIF | ![]() | 168 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 3l88C ![]() 2o39S S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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