[English] 日本語
Yorodumi- PDB-3l89: Human Adenovirus type 21 knob in complex with domains SCR1 and SC... -
+Open data
-Basic information
Entry | Database: PDB / ID: 3l89 | ||||||
---|---|---|---|---|---|---|---|
Title | Human Adenovirus type 21 knob in complex with domains SCR1 and SCR2 of CD46 (membrane cofactor protein, MCP) | ||||||
Components |
| ||||||
Keywords | VIRAL PROTEIN/PROTEIN BINDING / Adenovirus / Fiber Knob / Viral Protein / Membrane cofactor protein / MCP / virus receptor complex / SCR / Short consensus repeat / CCP / complement control protein / Complement pathway / Glycoprotein / Host-virus interaction / Immune response / Innate immunity / Sushi2 / VIRAL PROTEIN-PROTEIN BINDING complex | ||||||
Function / homology | Function and homology information sequestering of extracellular ligand from receptor / inner acrosomal membrane / negative regulation of complement activation, classical pathway / T cell mediated immunity / regulation of Notch signaling pathway / positive regulation of transforming growth factor beta production / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / adhesion receptor-mediated virion attachment to host cell / single fertilization ...sequestering of extracellular ligand from receptor / inner acrosomal membrane / negative regulation of complement activation, classical pathway / T cell mediated immunity / regulation of Notch signaling pathway / positive regulation of transforming growth factor beta production / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / adhesion receptor-mediated virion attachment to host cell / single fertilization / positive regulation of interleukin-10 production / complement activation, classical pathway / positive regulation of T cell proliferation / Regulation of Complement cascade / viral capsid / virus receptor activity / signaling receptor activity / adaptive immune response / cell adhesion / cadherin binding / symbiont entry into host cell / negative regulation of gene expression / focal adhesion / innate immune response / positive regulation of gene expression / cell surface / extracellular space / extracellular exosome / plasma membrane Similarity search - Function | ||||||
Biological species | Human adenovirus 21 Homo sapiens (human) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.5 Å | ||||||
Authors | Cupelli, K. / Stehle, T. | ||||||
Citation | Journal: J.Virol. / Year: 2010 Title: Structure of adenovirus type 21 knob in complex with CD46 reveals key differences in receptor contacts among species B adenoviruses. Authors: Cupelli, K. / Muller, S. / Persson, B.D. / Jost, M. / Arnberg, N. / Stehle, T. | ||||||
History |
|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
---|
-Downloads & links
-Download
PDBx/mmCIF format | 3l89.cif.gz | 699.7 KB | Display | PDBx/mmCIF format |
---|---|---|---|---|
PDB format | pdb3l89.ent.gz | 580.9 KB | Display | PDB format |
PDBx/mmJSON format | 3l89.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/l8/3l89 ftp://data.pdbj.org/pub/pdb/validation_reports/l8/3l89 | HTTPS FTP |
---|
-Related structure data
Related structure data | 3l88C 2o39S S: Starting model for refinement C: citing same article (ref.) |
---|---|
Similar structure data |
-Links
-Assembly
Deposited unit |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
4 |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Unit cell |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
|