Entry Database : PDB / ID : 3l15 Structure visualization Downloads & linksTitle Human Tead2 transcriptional factor ComponentsTranscriptional enhancer factor TEF-4 Details Keywords TRANSCRIPTION / Activator / DNA-binding / Nucleus / Transcription regulationFunction / homology Function and homology informationFunction Domain/homology Component
TEAD-YAP complex / lateral mesoderm development / RUNX3 regulates YAP1-mediated transcription / notochord development / YAP1- and WWTR1 (TAZ)-stimulated gene expression / paraxial mesoderm development / hippo signaling / regulation of stem cell differentiation / Formation of axial mesoderm / embryonic heart tube morphogenesis ... TEAD-YAP complex / lateral mesoderm development / RUNX3 regulates YAP1-mediated transcription / notochord development / YAP1- and WWTR1 (TAZ)-stimulated gene expression / paraxial mesoderm development / hippo signaling / regulation of stem cell differentiation / Formation of axial mesoderm / embryonic heart tube morphogenesis / vasculogenesis / embryonic organ development / cellular response to retinoic acid / neural tube closure / transcription coactivator binding / sequence-specific double-stranded DNA binding / disordered domain specific binding / protein-containing complex assembly / transcription regulator complex / transcription by RNA polymerase II / DNA-binding transcription factor activity, RNA polymerase II-specific / RNA polymerase II cis-regulatory region sequence-specific DNA binding / DNA-binding transcription factor activity / intracellular membrane-bounded organelle / regulation of DNA-templated transcription / chromatin / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / nucleoplasm / nucleus / cytosol Similarity search - Function Coagulation Factor XIII; Chain A, domain 1 - #80 / TEA/ATTS domain / Transcriptional enhancer factor, metazoa / TEA/ATTS domain superfamily / TEA/ATTS domain / TEA domain signature. / TEA domain profile. / TEA domain / YAP binding domain / YAP binding domain ... Coagulation Factor XIII; Chain A, domain 1 - #80 / TEA/ATTS domain / Transcriptional enhancer factor, metazoa / TEA/ATTS domain superfamily / TEA/ATTS domain / TEA domain signature. / TEA domain profile. / TEA domain / YAP binding domain / YAP binding domain / Coagulation Factor XIII; Chain A, domain 1 / Distorted Sandwich / Mainly Beta Similarity search - Domain/homologyBiological species Homo sapiens (human)Method X-RAY DIFFRACTION / SYNCHROTRON / SAD / Resolution : 2 Å DetailsAuthors Tomchick, D.R. / Luo, X. / Tian, W. Citation Show more 3 items Show less#1: Journal : DEV.CELL / Year : 2008Title : The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
Authors :
Wu, S. / Liu, Y. / Zheng, Y. / Dong, J. / Pan, D. #3: Journal : Genes Dev. / Year : 2008Title : TEAD mediates YAP-dependent gene induction and growth control.
Authors :
Zhao, B. / Ye, X. / Yu, J. / Li, L. / Li, W. / Li, S. / Lin, J.D. / Wang, C.Y. / Chinnaiyan, A.M. / Lai, Z.C. / Guan, K.L. History Deposition Dec 10, 2009 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Apr 7, 2010 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Version format complianceRevision 1.2 Nov 1, 2017 Group : Refinement description / Category : software
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