- PDB-3kfo: Crystal structure of the C-terminal domain from the nuclear pore ... -
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基本情報
登録情報
データベース: PDB / ID: 3kfo
タイトル
Crystal structure of the C-terminal domain from the nuclear pore complex component NUP133 from Saccharomyces cerevisiae
要素
Nucleoporin NUP133
キーワード
PROTEIN TRANSPORT / Nuclear pore complex / NUP133 / yeast / proteolysis / STRUCTURAL GENOMICS / PSI2 / PROTEIN STRUCTURE INITIATIVE / NEW YORK STRUCTURAL GENOMIX RESEARCH CONSORTIUM / NYSGXRC / Membrane / mRNA transport / Nucleus / Phosphoprotein / Translocation / Transport / New York SGX Research Center for Structural Genomics
機能・相同性
機能・相同性情報
mRNA export from nucleus in response to heat stress / nuclear pore localization / transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery / telomere tethering at nuclear periphery / nuclear pore outer ring / tRNA export from nucleus / Transport of Mature mRNA derived from an Intron-Containing Transcript / post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery / Regulation of HSF1-mediated heat shock response / SUMOylation of SUMOylation proteins ...mRNA export from nucleus in response to heat stress / nuclear pore localization / transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery / telomere tethering at nuclear periphery / nuclear pore outer ring / tRNA export from nucleus / Transport of Mature mRNA derived from an Intron-Containing Transcript / post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery / Regulation of HSF1-mediated heat shock response / SUMOylation of SUMOylation proteins / SUMOylation of RNA binding proteins / structural constituent of nuclear pore / SUMOylation of chromatin organization proteins / nucleocytoplasmic transport / silent mating-type cassette heterochromatin formation / poly(A)+ mRNA export from nucleus / subtelomeric heterochromatin formation / nuclear pore / protein import into nucleus / double-strand break repair / nuclear envelope / nuclear membrane / chromosome, telomeric region / positive regulation of DNA-templated transcription / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / nucleus / cytosol 類似検索 - 分子機能
Nuclear pore complex protein Nup133-like / Nucleoporin, Nup133/Nup155-like, C-terminal / Non-repetitive/WGA-negative nucleoporin C-terminal / Nucleoporin, Nup133/Nup155-like, N-terminal / Nup133 N terminal like / WD40/YVTN repeat-like-containing domain superfamily 類似検索 - ドメイン・相同性
N-TERMINAL RESIDUES ARE NOT DEFINED THE ELECTRON DENSITY DUE TO IN-CELL PROTEOLYSIS OF THE ...N-TERMINAL RESIDUES ARE NOT DEFINED THE ELECTRON DENSITY DUE TO IN-CELL PROTEOLYSIS OF THE ORIGINALLY DESIGNED CONSTRUCT.
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実験情報
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実験
実験
手法: X線回折 / 使用した結晶の数: 1
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試料調製
結晶化
温度: 294 K / 手法: 蒸気拡散法, シッティングドロップ法 詳細: 20% PEG 3350, 200mM Potassium Thiocyanate, VAPOR DIFFUSION, SITTING DROP, temperature 294K