- PDB-3jrr: Crystal structure of the ligand binding suppressor domain of type... -
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Basic information
Entry
Database: PDB / ID: 3jrr
Title
Crystal structure of the ligand binding suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor
Components
Inositol 1,4,5-trisphosphate receptor type 3
Keywords
TRANSPORT PROTEIN / beta-trefoil / Calcium channel / Calcium transport / Endoplasmic reticulum / Ion transport / Ionic channel / Membrane / Phosphoprotein / Receptor / Transmembrane / Transport
Function / homology
Function and homology information
Elevation of cytosolic Ca2+ levels / Effects of PIP2 hydrolysis / : / sensory perception of bitter taste / inositol 1,3,4,5 tetrakisphosphate binding / sensory perception of umami taste / inositol 1,4,5-trisphosphate-gated calcium channel activity / sensory perception of sweet taste / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / Glucagon-like Peptide-1 (GLP1) regulates insulin secretion ...Elevation of cytosolic Ca2+ levels / Effects of PIP2 hydrolysis / : / sensory perception of bitter taste / inositol 1,3,4,5 tetrakisphosphate binding / sensory perception of umami taste / inositol 1,4,5-trisphosphate-gated calcium channel activity / sensory perception of sweet taste / Antigen activates B Cell Receptor (BCR) leading to generation of second messengers / Glucagon-like Peptide-1 (GLP1) regulates insulin secretion / inositol hexakisphosphate binding / Ion homeostasis / inositol 1,4,5 trisphosphate binding / nuclear outer membrane / calcium ion transport into cytosol / intracellularly gated calcium channel activity / plasma membrane => GO:0005886 / brush border / release of sequestered calcium ion into cytosol / cellular response to cAMP / phosphatidylinositol binding / secretory granule membrane / sarcoplasmic reticulum / long-term synaptic potentiation / cytoplasmic vesicle membrane / memory / response to calcium ion / calcium ion transport / presynapse / apical part of cell / myelin sheath / nuclear envelope / positive regulation of cytosolic calcium ion concentration / receptor complex / G protein-coupled receptor signaling pathway / neuronal cell body / calcium ion binding / dendrite / protein-containing complex binding / endoplasmic reticulum membrane / nucleolus / perinuclear region of cytoplasm / endoplasmic reticulum / nucleoplasm / identical protein binding / nucleus / plasma membrane / cytoplasm Similarity search - Function
Inositol 1,4,5-trisphosphate receptor / RyR/IP3 receptor binding core, RIH domain superfamily / RyR/IP3R Homology associated domain / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / RyR and IP3R Homology associated / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / MIR motif / MIR domain ...Inositol 1,4,5-trisphosphate receptor / RyR/IP3 receptor binding core, RIH domain superfamily / RyR/IP3R Homology associated domain / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / RyR and IP3R Homology associated / Inositol 1,4,5-trisphosphate/ryanodine receptor / RIH domain / MIR motif / MIR domain / MIR domain profile. / Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases / Mir domain superfamily / Trefoil (Acidic Fibroblast Growth Factor, subunit A) - #50 / Trefoil (Acidic Fibroblast Growth Factor, subunit A) / Trefoil / Ion transport domain / Ion transport protein / Mainly Beta Similarity search - Domain/homology
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