登録情報 | データベース: PDB / ID: 3hn3 |
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タイトル | Human beta-glucuronidase at 1.7 A resolution |
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要素 | Beta-glucuronidase |
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キーワード | HYDROLASE / LYSOSOMAL ENZYME / ACID HYDROLASE / GLYCOSIDASE / Disease mutation / Glycoprotein / Lysosome / Mucopolysaccharidosis |
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機能・相同性 | 機能・相同性情報
MPS VII - Sly syndrome / chondroitin sulfate catabolic process / glycosaminoglycan catabolic process / Hyaluronan uptake and degradation / : / beta-glucuronidase / heparan sulfate proteoglycan catabolic process / beta-glucuronidase activity / HS-GAG degradation / hyaluronan catabolic process ...MPS VII - Sly syndrome / chondroitin sulfate catabolic process / glycosaminoglycan catabolic process / Hyaluronan uptake and degradation / : / beta-glucuronidase / heparan sulfate proteoglycan catabolic process / beta-glucuronidase activity / HS-GAG degradation / hyaluronan catabolic process / lysosomal lumen / azurophil granule lumen / carbohydrate binding / ficolin-1-rich granule lumen / carbohydrate metabolic process / protein domain specific binding / intracellular membrane-bounded organelle / signaling receptor binding / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region / membrane類似検索 - 分子機能 Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 ...Glycoside hydrolase, family 2, active site / Glycosyl hydrolases family 2 acid/base catalyst. / Glycoside hydrolase, family 2, conserved site / Glycosyl hydrolases family 2 signature 1. / Glycoside hydrolase, family 2 / Glycoside hydrolase family 2, catalytic domain / Glycosyl hydrolases family 2, TIM barrel domain / Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich / Glycosyl hydrolases family 2, sugar binding domain / Glycosyl hydrolases family 2 / Glycosyl hydrolases family 2, sugar binding domain / Beta-Galactosidase/glucuronidase domain superfamily / Galactose-binding domain-like / Galactose-binding-like domain superfamily / Glycosidases / Glycoside hydrolase superfamily / Jelly Rolls / Immunoglobulins / TIM Barrel / Alpha-Beta Barrel / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.7 Å |
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データ登録者 | Klei, H.E. / Ghosh, K. / Anumula, R. |
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引用 | ジャーナル: To be Published タイトル: Human beta-glucuronidasel at 1.7 A resolution 著者: Klei, H.E. / Ghosh, K. / Anumula, R. |
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履歴 | 登録 | 2009年5月29日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2009年12月1日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Non-polymer description / Version format compliance |
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改定 1.2 | 2017年10月4日 | Group: Advisory / Data collection / Refinement description カテゴリ: diffrn_detector / pdbx_unobs_or_zero_occ_atoms / software Item: _diffrn_detector.detector |
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改定 2.0 | 2020年7月29日 | Group: Advisory / Atomic model ...Advisory / Atomic model / Data collection / Derived calculations / Non-polymer description / Structure summary カテゴリ: atom_site / chem_comp ...atom_site / chem_comp / database_PDB_caveat / entity / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / pdbx_validate_chiral / struct_asym / struct_conn / struct_site / struct_site_gen Item: _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ..._atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.formula / _chem_comp.formula_weight / _chem_comp.id / _chem_comp.mon_nstd_flag / _chem_comp.name / _chem_comp.type / _pdbx_struct_assembly_gen.asym_id_list / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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