登録情報 | データベース: PDB / ID: 3dhe |
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タイトル | ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE COMPLEXED DEHYDROEPIANDROSTERONE |
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要素 | ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE |
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キーワード | OXIDOREDUCTASE / SHORT-CHAIN DEHYDROGENASE / STEROID / DEHYDROEPIANDROSTERONE / DHEA / ANDROGEN |
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機能・相同性 | 機能・相同性情報
17-beta-hydroxysteroid dehydrogenase (NADP+) activity / 3(or 17)beta-hydroxysteroid dehydrogenase / estradiol binding / estrogen biosynthetic process / testosterone dehydrogenase [NAD(P)+] activity / cellular response to metal ion / Estrogen biosynthesis / : / testosterone biosynthetic process / testosterone dehydrogenase (NAD+) activity ...17-beta-hydroxysteroid dehydrogenase (NADP+) activity / 3(or 17)beta-hydroxysteroid dehydrogenase / estradiol binding / estrogen biosynthetic process / testosterone dehydrogenase [NAD(P)+] activity / cellular response to metal ion / Estrogen biosynthesis / : / testosterone biosynthetic process / testosterone dehydrogenase (NAD+) activity / testosterone 17-beta-dehydrogenase (NADP+) activity / 17beta-estradiol 17-dehydrogenase / estradiol 17-beta-dehydrogenase [NAD(P)+] activity / steroid biosynthetic process / estrogen metabolic process / NADP+ binding / small molecule binding / lysosome organization / The canonical retinoid cycle in rods (twilight vision) / catalytic activity / adipose tissue development / skeletal muscle tissue development / steroid binding / bone development / NADP binding / gene expression / protein homodimerization activity / cytosol / cytoplasm類似検索 - 分子機能 17beta-dehydrogenase / short chain dehydrogenase / Short-chain dehydrogenase/reductase, conserved site / Short-chain dehydrogenases/reductases family signature. / Short-chain dehydrogenase/reductase SDR / NAD(P)-binding Rossmann-like Domain / NAD(P)-binding domain superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE / 17-beta-hydroxysteroid dehydrogenase type 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / DIFFERENCE FOURIER / 解像度: 2.3 Å |
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データ登録者 | Han, Q. / Campbell, R.L. / Gangloff, A. / Lin, S.X. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2000 タイトル: Dehydroepiandrosterone and dihydrotestosterone recognition by human estrogenic 17beta-hydroxysteroid dehydrogenase. C-18/c-19 steroid discrimination and enzyme-induced strain. 著者: Han, Q. / Campbell, R.L. / Gangloff, A. / Huang, Y.W. / Lin, S.X. |
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履歴 | 登録 | 1998年3月25日 | 処理サイト: BNL |
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改定 1.0 | 1999年9月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年3月25日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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改定 1.3 | 2018年4月4日 | Group: Data collection / Other / カテゴリ: diffrn_source / pdbx_database_status Item: _diffrn_source.type / _pdbx_database_status.process_site |
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改定 1.4 | 2018年4月11日 | Group: Data collection / カテゴリ: diffrn_source / Item: _diffrn_source.source |
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改定 1.5 | 2023年8月9日 | Group: Database references / Derived calculations / Refinement description カテゴリ: database_2 / pdbx_initial_refinement_model ...database_2 / pdbx_initial_refinement_model / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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