登録情報 | データベース: PDB / ID: 3blt |
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タイトル | Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site |
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要素 | Tyrosine-protein phosphatase yopH |
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キーワード | HYDROLASE / Co-valent binding / binding affinity / binding selectivity / Membrane / Outer membrane / Plasmid / Protein phosphatase / Secreted / Virulence |
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機能・相同性 | 機能・相同性情報
dephosphorylation / protein-tyrosine-phosphatase / protein tyrosine phosphatase activity / extracellular region類似検索 - 分子機能 Protein-tyrosine phosphatase, YopH, N-terminal / Protein-tyrosine phosphatase, YopH, N-terminal domain superfamily / YopH, N-terminal / Type III secreted modular tyrosine phosphatase, SptP/YopH / Protein tyrosine phosphatase superfamily / Protein-Tyrosine Phosphatase; Chain A / Protein tyrosine phosphatase, catalytic domain / PTP type protein phosphatase domain profile. / Protein-tyrosine phosphatase / Tyrosine-specific protein phosphatase, PTPase domain ...Protein-tyrosine phosphatase, YopH, N-terminal / Protein-tyrosine phosphatase, YopH, N-terminal domain superfamily / YopH, N-terminal / Type III secreted modular tyrosine phosphatase, SptP/YopH / Protein tyrosine phosphatase superfamily / Protein-Tyrosine Phosphatase; Chain A / Protein tyrosine phosphatase, catalytic domain / PTP type protein phosphatase domain profile. / Protein-tyrosine phosphatase / Tyrosine-specific protein phosphatase, PTPase domain / Protein-tyrosine phosphatase, catalytic / Protein tyrosine phosphatase, catalytic domain motif / Tyrosine specific protein phosphatases active site. / Protein-tyrosine phosphatase, active site / Tyrosine-specific protein phosphatases domain / Tyrosine specific protein phosphatases domain profile. / Protein-tyrosine phosphatase-like / Alpha-Beta Complex / Alpha Beta類似検索 - ドメイン・相同性 phenyl ethenesulfonate / Tyrosine-protein phosphatase YopH類似検索 - 構成要素 |
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生物種 | Yersinia enterocolitica (腸炎エルシニア) |
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手法 | X線回折 / フーリエ合成 / 解像度: 2.2 Å |
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データ登録者 | Liu, S. / Zhang, Z.-Y. |
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引用 | ジャーナル: J.Am.Chem.Soc. / 年: 2008 タイトル: Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases. 著者: Liu, S. / Zhou, B. / Yang, H. / He, Y. / Jiang, Z.X. / Kumar, S. / Wu, L. / Zhang, Z.Y. |
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履歴 | 登録 | 2007年12月11日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年2月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2018年1月24日 | Group: Structure summary / カテゴリ: audit_author / Item: _audit_author.name |
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改定 1.3 | 2023年8月30日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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