登録情報 | データベース: PDB / ID: 2z0e |
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タイトル | The crystal structure of human Atg4B- LC3(1-124) complex |
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要素 | - Cysteine protease ATG4B
- Microtubule-associated proteins 1A/1B light chain 3B
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キーワード | HYDROLASE/STRUCTURAL PROTEIN / papain-like fold / ubiquitin fold / HYDROLASE-STRUCTURAL PROTEIN COMPLEX |
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機能・相同性 | 機能・相同性情報
protein-phosphatidylethanolamide deconjugating activity / otolith mineralization completed early in development / Receptor Mediated Mitophagy / TBC/RABGAPs / Pexophagy / KEAP1-NFE2L2 pathway / PINK1-PRKN Mediated Mitophagy / Macroautophagy / protein delipidation / microautophagy ...protein-phosphatidylethanolamide deconjugating activity / otolith mineralization completed early in development / Receptor Mediated Mitophagy / TBC/RABGAPs / Pexophagy / KEAP1-NFE2L2 pathway / PINK1-PRKN Mediated Mitophagy / Macroautophagy / protein delipidation / microautophagy / ceramide binding / aggrephagy / mucus secretion / protein localization to phagophore assembly site / piecemeal microautophagy of the nucleus / phosphatidylethanolamine binding / cellular response to nitrogen starvation / microtubule associated complex / positive regulation of mucus secretion / autolysosome / Macroautophagy / axoneme / autophagosome membrane / autophagosome maturation / mitophagy / autophagosome assembly / autophagosome / endomembrane system / cysteine-type peptidase activity / cellular response to starvation / tubulin binding / establishment of localization in cell / mitochondrial membrane / macroautophagy / protein processing / autophagy / protein transport / presynapse / cytoplasmic vesicle / scaffold protein binding / microtubule binding / endopeptidase activity / microtubule / 加水分解酵素; プロテアーゼ; ペプチド結合加水分解酵素; システインプロテアーゼ / protein domain specific binding / axon / cysteine-type endopeptidase activity / neuronal cell body / ubiquitin protein ligase binding / dendrite / endoplasmic reticulum / mitochondrion / proteolysis / membrane / cytosol / cytoplasm類似検索 - 分子機能 Peptidase C54, catalytic domain / Cysteine protease ATG4, F-type LIR motif / ATG4, F-type LIR motif / Peptidase C54 / Peptidase family C54 / Autophagy protein Atg8 ubiquitin-like / Autophagy protein Atg8 ubiquitin like / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Papain-like cysteine peptidase superfamily / Ubiquitin-like (UB roll) ...Peptidase C54, catalytic domain / Cysteine protease ATG4, F-type LIR motif / ATG4, F-type LIR motif / Peptidase C54 / Peptidase family C54 / Autophagy protein Atg8 ubiquitin-like / Autophagy protein Atg8 ubiquitin like / Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 / Papain-like cysteine peptidase superfamily / Ubiquitin-like (UB roll) / Ubiquitin-like domain superfamily / Roll / Alpha Beta類似検索 - ドメイン・相同性 Microtubule-associated proteins 1A/1B light chain 3B / Cysteine protease ATG4B類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト)
![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.9 Å |
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データ登録者 | Satoo, K. / Noda, N.N. / Inagaki, F. |
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引用 | ジャーナル: Embo J. / 年: 2009 タイトル: The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. 著者: Satoo, K. / Noda, N.N. / Kumeta, H. / Fujioka, Y. / Mizushima, N. / Ohsumi, Y. / Inagaki, F. |
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履歴 | 登録 | 2007年5月7日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2007年5月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2021年11月10日 | Group: Database references / カテゴリ: database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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改定 1.4 | 2023年11月1日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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