- PDB-2yuc: Solution structure of the TRAF-type zinc finger domains (102-164)... -
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基本情報
登録情報
データベース: PDB / ID: 2yuc
タイトル
Solution structure of the TRAF-type zinc finger domains (102-164) from human TNF receptor associated factor 4
要素
TNF receptor-associated factor 4
キーワード
SIGNALING PROTEIN / zf-TRAF / Cysteine-rich domain associated with RING and Traf domains protein 1 / Malignant 62 / RING finger protein 83 / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI
機能・相同性
機能・相同性情報
respiratory tube development / WW domain binding / respiratory gaseous exchange by respiratory system / thioesterase binding / tumor necrosis factor receptor binding / regulation of canonical NF-kappaB signal transduction / protein K63-linked ubiquitination / bicellular tight junction / positive regulation of protein kinase activity / tumor necrosis factor-mediated signaling pathway ...respiratory tube development / WW domain binding / respiratory gaseous exchange by respiratory system / thioesterase binding / tumor necrosis factor receptor binding / regulation of canonical NF-kappaB signal transduction / protein K63-linked ubiquitination / bicellular tight junction / positive regulation of protein kinase activity / tumor necrosis factor-mediated signaling pathway / positive regulation of JNK cascade / RING-type E3 ubiquitin transferase / fibrillar center / transferase activity / regulation of apoptotic process / proteasome-mediated ubiquitin-dependent protein catabolic process / cytoskeleton / innate immune response / apoptotic process / ubiquitin protein ligase binding / protein kinase binding / perinuclear region of cytoplasm / zinc ion binding / nucleoplasm / identical protein binding / nucleus / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能
手法: torsion angle dynamics / ソフトェア番号: 1 詳細: The structures are based on a total of 918 restraints, 870 are NOE-derived distance constraints, 48 dihedral angle restraints.
代表構造
選択基準: lowest energy
NMRアンサンブル
コンフォーマー選択の基準: structures with the least restraint violations, target function 計算したコンフォーマーの数: 100 / 登録したコンフォーマーの数: 20