Entry Database : PDB / ID : 2wry Structure visualization Downloads & linksTitle Crystal structure of chicken cytokine interleukin 1 beta ComponentsINTERLEUKIN-1BETA Details Keywords IMMUNE SYSTEM / PYROGEN / MITOGEN / INFLAMMATORY RESPONSEFunction / homology Function and homology informationFunction Domain/homology Component
chemokine production / Interleukin-1 processing / Pyroptosis / Interleukin-1 signaling / cortisol secretion / leukocyte activation involved in inflammatory response / leukocyte chemotaxis involved in inflammatory response / detection of lipopolysaccharide / regulation of non-canonical NF-kappaB signal transduction / sexual reproduction ... chemokine production / Interleukin-1 processing / Pyroptosis / Interleukin-1 signaling / cortisol secretion / leukocyte activation involved in inflammatory response / leukocyte chemotaxis involved in inflammatory response / detection of lipopolysaccharide / regulation of non-canonical NF-kappaB signal transduction / sexual reproduction / positive regulation of immature T cell proliferation in thymus / fever generation / neutrophil activation / interleukin-1 receptor binding / inflammatory response to antigenic stimulus / cellular response to cold / toll-like receptor signaling pathway / macrophage chemotaxis / cytokine activity / acute-phase response / response to virus / cytokine-mediated signaling pathway / positive regulation of inflammatory response / cellular response to lipopolysaccharide / lysosome / inflammatory response / positive regulation of gene expression / extracellular space / cytosol Similarity search - Function Interleukin-1 conserved site / Interleukin-1 signature. / Interleukin-1 homologues / Interleukin-1 family / Interleukin-1 / 18 / Cytokine IL1/FGF / Trefoil (Acidic Fibroblast Growth Factor, subunit A) - #50 / Trefoil (Acidic Fibroblast Growth Factor, subunit A) / Trefoil / Mainly Beta Similarity search - Domain/homologyBiological species GALLUS GALLUS (chicken)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.58 Å DetailsAuthors Lu, W.S. / Cheng, C.S. / Lyu, P.C. / Lee, L.H. / Wang, W.C. / Yin, H.S. CitationJournal : Mol.Immunol. / Year : 2011Title : Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human.Authors : Cheng, C.S. / Chen, W.T. / Lee, L.H. / Chen, Y.W. / Chang, S.Y. / Lyu, P.C. / Yin, H.S. History Deposition Sep 3, 2009 Deposition site : PDBE / Processing site : PDBERevision 1.0 Sep 29, 2010 Provider : repository / Type : Initial releaseRevision 1.1 May 8, 2011 Group : Version format complianceRevision 1.2 Jul 13, 2011 Group : Version format complianceRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_sheet Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_sheet.number_strands
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