登録情報 | データベース: PDB / ID: 2wb8 |
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タイトル | Crystal structure of Haspin kinase |
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要素 | SERINE/THREONINE-PROTEIN KINASE HASPIN |
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キーワード | TRANSFERASE / HISTONE MODIFICATION / PHOSPHOPROTEIN / ATYPICAL KINASE / SERINE/THREONINE-PROTEIN KINASE / NUCLEOTIDE-BINDING / CHROMATIN REGULATOR / CELL CYCLE / HISTONE H3 / ATP-BINDING / GSG2 / KINASE / HASPIN / NUCLEUS / MITOSIS |
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機能・相同性 | 機能・相同性情報
histone H3T3 kinase activity / protein localization to chromosome, centromeric region / mitotic sister chromatid cohesion / mitotic spindle assembly checkpoint signaling / spindle / chromosome / mitotic cell cycle / non-specific serine/threonine protein kinase / protein kinase activity / intracellular signal transduction ...histone H3T3 kinase activity / protein localization to chromosome, centromeric region / mitotic sister chromatid cohesion / mitotic spindle assembly checkpoint signaling / spindle / chromosome / mitotic cell cycle / non-specific serine/threonine protein kinase / protein kinase activity / intracellular signal transduction / protein phosphorylation / protein serine kinase activity / centrosome / nucleoplasm / ATP binding / nucleus / cytoplasm類似検索 - 分子機能 Serine/threonine-protein kinase haspin, C-terminal / Domain of unknown function / Haspin like kinase domain / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. ...Serine/threonine-protein kinase haspin, C-terminal / Domain of unknown function / Haspin like kinase domain / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / Phosphorylase Kinase; domain 1 / Phosphorylase Kinase; domain 1 / Serine/Threonine protein kinases, catalytic domain / Protein kinase, ATP binding site / Protein kinases ATP-binding region signature. / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | HOMO SAPIENS (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.15 Å |
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データ登録者 | Villa, F. / Tortorci, M. / Forneris, F. / Mattevi, A. / Musacchio, A. |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2009 タイトル: Crystal Structure of the Catalytic Domain of Haspin, an Atypical Kinase Implicated in Chromatin Organization. 著者: Villa, F. / Capasso, P. / Tortorici, M. / Forneris, F. / De Marco, A. / Mattevi, A. / Musacchio, A. |
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履歴 | 登録 | 2009年2月23日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2009年11月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Advisory / Version format compliance |
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改定 1.2 | 2024年5月8日 | Group: Data collection / Database references / Other カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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