登録情報 データベース : PDB / ID : 2vz2 構造の表示 ダウンロードとリンクタイトル Human MAO B in complex with mofegiline 要素AMINE OXIDASE [FLAVIN-CONTAINING] B 詳細 キーワード OXIDOREDUCTASE / INHIBITOR BINDING / FLAVOPROTEIN / MITOCHONDRION / TRANSMEMBRANE / HUMAN MONOAMINE OXIDASE / MITOCHONDRION OUTER MEMBRANE / FAD / FLAVIN / MEMBRANE / MOFEGILINE / ACETYLATION機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase / monoamine oxidase activity / primary-amine oxidase / primary methylamine oxidase activity / dopamine catabolic process / mitochondrial envelope / hydrogen peroxide biosynthetic process / substantia nigra development / flavin adenine dinucleotide binding ... Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB / monoamine oxidase / monoamine oxidase activity / primary-amine oxidase / primary methylamine oxidase activity / dopamine catabolic process / mitochondrial envelope / hydrogen peroxide biosynthetic process / substantia nigra development / flavin adenine dinucleotide binding / mitochondrial outer membrane / electron transfer activity / mitochondrion 類似検索 - 分子機能 Guanine Nucleotide Dissociation Inhibitor, domain 1 / Guanine Nucleotide Dissociation Inhibitor; domain 1 / : / Polyamine Oxidase; Chain A, domain 2 - #10 / Flavin amine oxidase / Polyamine Oxidase; Chain A, domain 2 / Amine oxidase / Flavin containing amine oxidoreductase / FAD/NAD(P)-binding domain / FAD/NAD(P)-binding domain ... Guanine Nucleotide Dissociation Inhibitor, domain 1 / Guanine Nucleotide Dissociation Inhibitor; domain 1 / : / Polyamine Oxidase; Chain A, domain 2 - #10 / Flavin amine oxidase / Polyamine Oxidase; Chain A, domain 2 / Amine oxidase / Flavin containing amine oxidoreductase / FAD/NAD(P)-binding domain / FAD/NAD(P)-binding domain / 3-Layer(bba) Sandwich / FAD/NAD(P)-binding domain superfamily / Alpha-Beta Complex / Orthogonal Bundle / Mainly Alpha / Alpha Beta 類似検索 - ドメイン・相同性 Chem-C15 / FLAVIN-ADENINE DINUCLEOTIDE / Chem-MFG / Amine oxidase [flavin-containing] B 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.3 Å 詳細データ登録者 Bonivento, D. / Mattevi, A. 引用ジャーナル : J. Med. Chem. / 年 : 2008タイトル : Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.著者 : Milczek, E.M. / Bonivento, D. / Binda, C. / Mattevi, A. / McDonald, I.A. / Edmondson, D.E. 履歴 登録 2008年7月29日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2008年12月16日 Provider : repository / タイプ : Initial release改定 1.1 2011年5月7日 Group : Version format compliance改定 1.2 2011年7月13日 Group : Version format compliance改定 1.3 2018年2月28日 Group : Database references / Structure summary / カテゴリ : citation / citation_author / structItem : _citation.journal_abbrev / _citation.journal_id_ISSN ... _citation.journal_abbrev / _citation.journal_id_ISSN / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation_author.name / _struct.title 改定 1.4 2023年12月13日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_special_symmetry / struct_conn / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flag / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id 改定 1.5 2024年11月6日 Group : Structure summaryカテゴリ : pdbx_entry_details / pdbx_modification_featureItem : _pdbx_entry_details.has_protein_modification
すべて表示 表示を減らす Remark 700 SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.