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- PDB-2qy0: Active dimeric structure of the catalytic domain of C1r reveals e... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2qy0 | ||||||
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Title | Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts | ||||||
![]() | (Complement C1r subcomponent) x 2 | ||||||
![]() | HYDROLASE / complement / serine protease / beta barrel / Complement pathway / EGF-like domain / Glycoprotein / Hydroxylation / Immune response / Innate immunity / Phosphorylation / Sushi | ||||||
Function / homology | ![]() complement subcomponent C_overbar_1r_ / molecular sequestering activity / zymogen activation / Classical antibody-mediated complement activation / Initial triggering of complement / serine-type peptidase activity / complement activation, classical pathway / Regulation of Complement cascade / blood microparticle / immune response ...complement subcomponent C_overbar_1r_ / molecular sequestering activity / zymogen activation / Classical antibody-mediated complement activation / Initial triggering of complement / serine-type peptidase activity / complement activation, classical pathway / Regulation of Complement cascade / blood microparticle / immune response / serine-type endopeptidase activity / innate immune response / calcium ion binding / extracellular space / extracellular exosome / extracellular region / identical protein binding Similarity search - Function | ||||||
Biological species | ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Kardos, J. / Harmat, V. / Pallo, A. / Barabas, O. / Szilagyi, K. / Graf, L. / Naray-Szabo, G. / Goto, Y. / Zavodszky, P. / Gal, P. | ||||||
![]() | ![]() Title: Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r. Authors: Kardos, J. / Harmat, V. / Pallo, A. / Barabas, O. / Szilagyi, K. / Graf, L. / Naray-Szabo, G. / Goto, Y. / Zavodszky, P. / Gal, P. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 168.6 KB | Display | ![]() |
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PDB format | ![]() | 132.4 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
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-Validation report
Summary document | ![]() | 468.6 KB | Display | ![]() |
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Full document | ![]() | 478.4 KB | Display | |
Data in XML | ![]() | 31.3 KB | Display | |
Data in CIF | ![]() | 43.8 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 1gpzS S: Starting model for refinement |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Refine code: 4
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