登録情報 | データベース: PDB / ID: 2ovj |
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タイトル | The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP. |
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要素 | Rac GTPase-activating protein 1 |
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キーワード | SIGNALING PROTEIN / Structural Genomics / Structural Genomics Consortium / SGC |
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機能・相同性 | 機能・相同性情報
centralspindlin complex / actomyosin contractile ring assembly / sulfate transport / mitotic spindle midzone assembly / regulation of attachment of spindle microtubules to kinetochore / gamma-tubulin binding / RHOD GTPase cycle / Flemming body / Kinesins / regulation of small GTPase mediated signal transduction ...centralspindlin complex / actomyosin contractile ring assembly / sulfate transport / mitotic spindle midzone assembly / regulation of attachment of spindle microtubules to kinetochore / gamma-tubulin binding / RHOD GTPase cycle / Flemming body / Kinesins / regulation of small GTPase mediated signal transduction / COPI-dependent Golgi-to-ER retrograde traffic / RHOB GTPase cycle / beta-tubulin binding / RHOC GTPase cycle / positive regulation of cytokinesis / phosphatidylinositol-3,4,5-trisphosphate binding / cleavage furrow / regulation of embryonic development / CDC42 GTPase cycle / Rho protein signal transduction / mitotic cytokinesis / alpha-tubulin binding / RHOA GTPase cycle / neuroblast proliferation / RAC2 GTPase cycle / RAC3 GTPase cycle / spindle midzone / monoatomic ion transport / RAC1 GTPase cycle / MHC class II antigen presentation / erythrocyte differentiation / GTPase activator activity / acrosomal vesicle / cytoplasmic side of plasma membrane / mitotic spindle / spindle / protein-macromolecule adaptor activity / midbody / spermatogenesis / microtubule binding / microtubule / protein kinase binding / extracellular exosome / nucleoplasm / nucleus / metal ion binding / cytosol類似検索 - 分子機能 Phosphatidylinositol 3-kinase; Chain A / Rho GTPase activation protein / Rho GTPase-activating protein domain / RhoGAP domain / Rho GTPase-activating proteins domain profile. / GTPase-activator protein for Rho-like GTPases / Phorbol esters/diacylglycerol binding domain (C1 domain) / Rho GTPase activation protein / Zinc finger phorbol-ester/DAG-type signature. / Zinc finger phorbol-ester/DAG-type profile. ...Phosphatidylinositol 3-kinase; Chain A / Rho GTPase activation protein / Rho GTPase-activating protein domain / RhoGAP domain / Rho GTPase-activating proteins domain profile. / GTPase-activator protein for Rho-like GTPases / Phorbol esters/diacylglycerol binding domain (C1 domain) / Rho GTPase activation protein / Zinc finger phorbol-ester/DAG-type signature. / Zinc finger phorbol-ester/DAG-type profile. / Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains) / Protein kinase C-like, phorbol ester/diacylglycerol-binding domain / C1-like domain superfamily / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.49 Å |
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データ登録者 | Shrestha, L. / Papagrigoriou, E. / Soundararajan, M. / Elkins, J. / Johansson, C. / von Delft, F. / Pike, A.C.W. / Burgess, N. / Turnbull, A. / Debreczeni, J. ...Shrestha, L. / Papagrigoriou, E. / Soundararajan, M. / Elkins, J. / Johansson, C. / von Delft, F. / Pike, A.C.W. / Burgess, N. / Turnbull, A. / Debreczeni, J. / Gorrec, F. / Umeano, C. / Edwards, A. / Arrowsmith, C.H. / Weigelt, J. / Sundstrom, M. / Doyle, D.A. / Structural Genomics Consortium (SGC) |
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引用 | ジャーナル: To be Published タイトル: The crystal structure of the human Rac GTPase activating protein 1 (RACGAP1) MgcRacGAP. 著者: Shrestha, L. / Papagrigoriou, E. / Soundararajan, M. / Elkins, J. / Johansson, C. / von Delft, F. / Pike, A.C.W. / Burgess, N. / Turnbull, A. / Debreczeni, J. / Gorrec, F. / Umeano, C. / ...著者: Shrestha, L. / Papagrigoriou, E. / Soundararajan, M. / Elkins, J. / Johansson, C. / von Delft, F. / Pike, A.C.W. / Burgess, N. / Turnbull, A. / Debreczeni, J. / Gorrec, F. / Umeano, C. / Edwards, A. / Arrowsmith, C.H. / Weigelt, J. / Sundstrom, M. / Doyle, D.A. |
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履歴 | 登録 | 2007年2月14日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2007年2月27日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Advisory / Version format compliance |
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改定 1.3 | 2017年10月18日 | Group: Refinement description / カテゴリ: software / Item: _software.name |
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改定 1.4 | 2023年8月30日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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