Entry | Database: PDB / ID: 2n2n |
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Title | Tom1 negatively modulates binding of Tollip to phosphatidylinositol 3-phosphate via a coupled folding and binding mechanism |
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Components | Target of Myb protein 1 |
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Keywords | PROTEIN TRANSPORT |
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Function / homology | Function and homology information
myosin VI binding / substrate localization to autophagosome / regulation of endosome organization / clathrin heavy chain binding / phosphatidylinositol-5-phosphate binding / autophagosome-lysosome fusion / positive regulation of autophagosome maturation / azurophil granule membrane / endosomal transport / clathrin binding ...myosin VI binding / substrate localization to autophagosome / regulation of endosome organization / clathrin heavy chain binding / phosphatidylinositol-5-phosphate binding / autophagosome-lysosome fusion / positive regulation of autophagosome maturation / azurophil granule membrane / endosomal transport / clathrin binding / polyubiquitin modification-dependent protein binding / specific granule membrane / ubiquitin binding / endocytosis / protein transport / early endosome membrane / endosome / endosome membrane / early endosome / Neutrophil degranulation / signal transduction / extracellular exosome / membrane / plasma membrane / cytoplasm / cytosolSimilarity search - Function Target of Myb protein 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #160 / GAT domain / GAT domain superfamily / GAT domain / GAT domain profile. / VHS domain / VHS domain / VHS domain profile. / Domain present in VPS-27, Hrs and STAM ...Target of Myb protein 1 / Methane Monooxygenase Hydroxylase; Chain G, domain 1 - #160 / GAT domain / GAT domain superfamily / GAT domain / GAT domain profile. / VHS domain / VHS domain / VHS domain profile. / Domain present in VPS-27, Hrs and STAM / ENTH/VHS / Methane Monooxygenase Hydroxylase; Chain G, domain 1 / Up-down Bundle / Mainly AlphaSimilarity search - Domain/homology |
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Biological species | Homo sapiens (human) |
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Method | SOLUTION NMR / DISTANCE GEOMETRY, SIMULATED ANNEALING |
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Model details | score result from Rosetta, model1 |
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Authors | Xiao, S. / Armstrong, G. / Capelluto, D. |
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Citation | Journal: Structure / Year: 2015 Title: Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. Authors: Xiao, S. / Brannon, M.K. / Zhao, X. / Fread, K.I. / Ellena, J.F. / Bushweller, J.H. / Finkielstein, C.V. / Armstrong, G.S. / Capelluto, D.G. |
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History | Deposition | May 11, 2015 | Deposition site: BMRB / Processing site: RCSB |
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Revision 1.0 | Sep 16, 2015 | Provider: repository / Type: Initial release |
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Revision 1.1 | Oct 21, 2015 | Group: Database references |
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Revision 1.2 | Jun 14, 2023 | Group: Data collection / Database references / Other Category: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_nmr_spectrometer / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
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Revision 1.3 | May 15, 2024 | Group: Data collection / Database references / Category: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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